ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Signal recognition particle subunit SRP72

Intramolecular
Cysteine 50 and cysteine 54
A redox-regulated disulphide may form within Signal recognition particle subunit SRP72 between cysteines 50 and 54. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
53
PDB code
5wrw
Structure name
structure of human apo-srp72
Structure deposition date
2016-12-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
72
Minimum pKa ?
11
% buried
72
Peptide accession
O76094
Residue number A
50
Residue number B
54
Peptide name
Signal recognition particle subunit SRP72

Ligandability

Cysteine 50 of Signal recognition particle subunit SRP72

Cysteine 54 of Signal recognition particle subunit SRP72

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