a tool for identifying drug-targetable redox-active disulphides

Tumor necrosis factor ligand superfamily member 15

Intramolecular

Cysteine 162 and cysteine 202

A redox-regulated disulphide may form within Tumor necrosis factor ligand superfamily member 15 between cysteines 162 and 202.

Details

Redox score ?

82

PDB code

Structure name

crystal structure of tl1a

Structure deposition date

2006-11-27

Thiol separation (Å)

3

Half-sphere exposure sum ?

nan

Minimum pK_a ?

9

% buried

13

Peptide accession

Residue number A

162

Residue number B

202

Peptide name

Tumor necrosis factor ligand superfamily member 15

Ligandability

Cysteine 162 of Tumor necrosis factor ligand superfamily member 15

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 202 of Tumor necrosis factor ligand superfamily member 15

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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