ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

Intermolecular
Cysteine 144 and cysteine 279 of NADH-ubiquinone oxidoreductase chain 5
A redox-regulated disulphide may form between cysteine 144 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial and cysteine 279 of NADH-ubiquinone oxidoreductase chain 5.

Details

Redox score ?
81
PDB code
5xtc
Structure name
cryo-em structure of human respiratory complex i transmembrane arm
Structure deposition date
2017-06-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide A name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
Peptide B name
NADH-ubiquinone oxidoreductase chain 5
Peptide A accession
O95169
Peptide B accession
X5BVZ3
Peptide A residue number
144
Peptide B residue number
279

Ligandability

Cysteine 144 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

Cysteine 279 of NADH-ubiquinone oxidoreductase chain 5

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