Growth arrest and DNA damage-inducible protein GADD45 gamma
Intramolecular
Cysteine 60 and cysteine 119
Cysteine 60 and cysteine 85
Cysteine 85 and cysteine 86
Cysteine 85 and cysteine 119
Cysteine 60 and cysteine 86
Cysteine 86 and cysteine 142
3ffm A 60 A 119
A redox-regulated disulphide may form within Growth arrest and DNA damage-inducible protein GADD45 gamma between cysteines 60 and 119.
Details
Redox score ?
68
PDB code
3ffm
Structure name
the crystal structure of human gadd45g
Structure deposition date
2008-12-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
91
Minimum pKa ?
8
% buried
95
Peptide accession
O95257
Residue number A
60
Residue number B
119
Peptide name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Ligandability
Cysteine 60 of Growth arrest and DNA damage-inducible protein GADD45 gamma
Cysteine 119 of Growth arrest and DNA damage-inducible protein GADD45 gamma
2wal B 60 B 85
A redox-regulated disulphide may form within Growth arrest and DNA damage-inducible protein GADD45 gamma between cysteines 60 and 85.
Details
Redox score ?
67
PDB code
2wal
Structure name
crystal structure of human gadd45gamma
Structure deposition date
2009-02-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
83
Minimum pKa ?
9
% buried
96
Peptide accession
O95257
Residue number A
60
Residue number B
85
Peptide name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Ligandability
Cysteine 60 of Growth arrest and DNA damage-inducible protein GADD45 gamma
Cysteine 85 of Growth arrest and DNA damage-inducible protein GADD45 gamma
2wal A 85 A 86
A redox-regulated disulphide may form within Growth arrest and DNA damage-inducible protein GADD45 gamma between cysteines 85 and 86. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
2wal
Structure name
crystal structure of human gadd45gamma
Structure deposition date
2009-02-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
62
Minimum pKa ?
9
% buried
82
Peptide accession
O95257
Residue number A
85
Residue number B
86
Peptide name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Ligandability
Cysteine 85 of Growth arrest and DNA damage-inducible protein GADD45 gamma
Cysteine 86 of Growth arrest and DNA damage-inducible protein GADD45 gamma
2wal B 85 B 119
A redox-regulated disulphide may form within Growth arrest and DNA damage-inducible protein GADD45 gamma between cysteines 85 and 119. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
2wal
Structure name
crystal structure of human gadd45gamma
Structure deposition date
2009-02-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
77
Minimum pKa ?
8
% buried
90
Peptide accession
O95257
Residue number A
85
Residue number B
119
Peptide name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Ligandability
Cysteine 85 of Growth arrest and DNA damage-inducible protein GADD45 gamma
Cysteine 119 of Growth arrest and DNA damage-inducible protein GADD45 gamma
3ffm A 60 A 86
A redox-regulated disulphide may form within Growth arrest and DNA damage-inducible protein GADD45 gamma between cysteines 60 and 86. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
3ffm
Structure name
the crystal structure of human gadd45g
Structure deposition date
2008-12-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
10
% buried
62
Peptide accession
O95257
Residue number A
60
Residue number B
86
Peptide name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Ligandability
Cysteine 60 of Growth arrest and DNA damage-inducible protein GADD45 gamma
Cysteine 86 of Growth arrest and DNA damage-inducible protein GADD45 gamma
3ffm A 86 A 142
A redox-regulated disulphide may form within Growth arrest and DNA damage-inducible protein GADD45 gamma between cysteines 86 and 142. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
3ffm
Structure name
the crystal structure of human gadd45g
Structure deposition date
2008-12-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
48
Peptide accession
O95257
Residue number A
86
Residue number B
142
Peptide name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Ligandability
Cysteine 86 of Growth arrest and DNA damage-inducible protein GADD45 gamma
Cysteine 142 of Growth arrest and DNA damage-inducible protein GADD45 gamma
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