a tool for identifying drug-targetable redox-active disulphides

Myelin protein zero-like protein 1

Intramolecular

Cysteine 58 and cysteine 135

A redox-regulated disulphide may form within Myelin protein zero-like protein 1 between cysteines 58 and 135.

Details

Redox score ?

76

PDB code

Structure name

crystal structure of myelin protein zero-like protein 1 (mpzl1)

Structure deposition date

2018-09-25

Thiol separation (Å)

3

Half-sphere exposure sum ?

77

Minimum pK_a ?

8

% buried

84

Peptide accession

Residue number A

58

Residue number B

135

Peptide name

Myelin protein zero-like protein 1

Ligandability

Cysteine 58 of Myelin protein zero-like protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 135 of Myelin protein zero-like protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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