Claudin-9
Intramolecular
Cysteine 25 and cysteine 84
Cysteine 54 and cysteine 64
Cysteine 182 and cysteine 185
Cysteine 182 and cysteine 183
Cysteine 104 and cysteine 107
Cysteine 183 and cysteine 185
6ov2 A 25 A 84
A redox-regulated disulphide may form within Claudin-9 between cysteines 25 and 84.
Details
Redox score ?
81
PDB code
6ov2
Structure name
crystal structure of human claudin-9 in complex with clostridium perfringens entertoxin c-terminal domain in closed form
Structure deposition date
2019-05-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95484
Residue number A
25
Residue number B
84
Peptide name
Claudin-9
Ligandability
Cysteine 25 of Claudin-9
Cysteine 84 of Claudin-9
6ov2 A 54 A 64
A redox-regulated disulphide may form within Claudin-9 between cysteines 54 and 64.
Details
Redox score ?
80
PDB code
6ov2
Structure name
crystal structure of human claudin-9 in complex with clostridium perfringens entertoxin c-terminal domain in closed form
Structure deposition date
2019-05-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95484
Residue number A
54
Residue number B
64
Peptide name
Claudin-9
Ligandability
Cysteine 54 of Claudin-9
Cysteine 64 of Claudin-9
6ov3 A 182 A 185
A redox-regulated disulphide may form within Claudin-9 between cysteines 182 and 185. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
6ov3
Structure name
crystal structure of human claudin-9 in complex with clostridium perfringens entertoxin c-terminal domain in open form
Structure deposition date
2019-05-06
Thiol separation (Å)
8
Half-sphere exposure sum ?
44
Minimum pKa ?
9
% buried
3
Peptide accession
O95484
Residue number A
182
Residue number B
185
Peptide name
Claudin-9
Ligandability
Cysteine 182 of Claudin-9
Cysteine 185 of Claudin-9
6ov3 A 182 A 183
A redox-regulated disulphide may form within Claudin-9 between cysteines 182 and 183. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
6ov3
Structure name
crystal structure of human claudin-9 in complex with clostridium perfringens entertoxin c-terminal domain in open form
Structure deposition date
2019-05-06
Thiol separation (Å)
8
Half-sphere exposure sum ?
43
Minimum pKa ?
9
% buried
3
Peptide accession
O95484
Residue number A
182
Residue number B
183
Peptide name
Claudin-9
Ligandability
Cysteine 182 of Claudin-9
Cysteine 183 of Claudin-9
6ov2 A 104 A 107
A redox-regulated disulphide may form within Claudin-9 between cysteines 104 and 107. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
6ov2
Structure name
crystal structure of human claudin-9 in complex with clostridium perfringens entertoxin c-terminal domain in closed form
Structure deposition date
2019-05-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
32
Minimum pKa ?
9
% buried
0
Peptide accession
O95484
Residue number A
104
Residue number B
107
Peptide name
Claudin-9
Ligandability
Cysteine 104 of Claudin-9
Cysteine 107 of Claudin-9
6ov2 A 183 A 185
A redox-regulated disulphide may form within Claudin-9 between cysteines 183 and 185. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
6ov2
Structure name
crystal structure of human claudin-9 in complex with clostridium perfringens entertoxin c-terminal domain in closed form
Structure deposition date
2019-05-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
31
Minimum pKa ?
9
% buried
0
Peptide accession
O95484
Residue number A
183
Residue number B
185
Peptide name
Claudin-9
Ligandability
Cysteine 183 of Claudin-9
Cysteine 185 of Claudin-9
If this tool was useful for finding a disulphide, please cite: