Adhesion G protein-coupled receptor L2
Intramolecular
Cysteine 84 and cysteine 116
Cysteine 97 and cysteine 103
Cysteine 51 and cysteine 129
Cysteine 42 and cysteine 72
Cysteine 51 and cysteine 97
Cysteine 51 and cysteine 103
6ske D 55 D 87
A redox-regulated disulphide may form within Adhesion G protein-coupled receptor L2 between cysteines 84 and 116 (55 and 87 respectively in this structure).
Details
Redox score ?
88
PDB code
6ske
Structure name
teneurin 2 in complex with latrophilin 2 lec domain
Structure deposition date
2019-08-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8JZZ7
Residue number A
84
Residue number B
116
Peptide name
Adhesion G protein-coupled receptor L2
Ligandability
Cysteine 84 of Adhesion G protein-coupled receptor L2
Cysteine 116 of Adhesion G protein-coupled receptor L2
6ske B 68 B 74
A redox-regulated disulphide may form within Adhesion G protein-coupled receptor L2 between cysteines 97 and 103 (68 and 74 respectively in this structure).
Details
Redox score ?
86
PDB code
6ske
Structure name
teneurin 2 in complex with latrophilin 2 lec domain
Structure deposition date
2019-08-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8JZZ7
Residue number A
97
Residue number B
103
Peptide name
Adhesion G protein-coupled receptor L2
Ligandability
Cysteine 97 of Adhesion G protein-coupled receptor L2
Cysteine 103 of Adhesion G protein-coupled receptor L2
6ske D 22 D 100
A redox-regulated disulphide may form within Adhesion G protein-coupled receptor L2 between cysteines 51 and 129 (22 and 100 respectively in this structure).
Details
Redox score ?
84
PDB code
6ske
Structure name
teneurin 2 in complex with latrophilin 2 lec domain
Structure deposition date
2019-08-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8JZZ7
Residue number A
51
Residue number B
129
Peptide name
Adhesion G protein-coupled receptor L2
Ligandability
Cysteine 51 of Adhesion G protein-coupled receptor L2
Cysteine 129 of Adhesion G protein-coupled receptor L2
6ske B 13 B 43
A redox-regulated disulphide may form within Adhesion G protein-coupled receptor L2 between cysteines 42 and 72 (13 and 43 respectively in this structure).
Details
Redox score ?
80
PDB code
6ske
Structure name
teneurin 2 in complex with latrophilin 2 lec domain
Structure deposition date
2019-08-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8JZZ7
Residue number A
42
Residue number B
72
Peptide name
Adhesion G protein-coupled receptor L2
Ligandability
Cysteine 42 of Adhesion G protein-coupled receptor L2
Cysteine 72 of Adhesion G protein-coupled receptor L2
6ske D 22 D 68
A redox-regulated disulphide may form within Adhesion G protein-coupled receptor L2 between cysteines 51 and 97 (22 and 68 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
6ske
Structure name
teneurin 2 in complex with latrophilin 2 lec domain
Structure deposition date
2019-08-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8JZZ7
Residue number A
51
Residue number B
97
Peptide name
Adhesion G protein-coupled receptor L2
Ligandability
Cysteine 51 of Adhesion G protein-coupled receptor L2
Cysteine 97 of Adhesion G protein-coupled receptor L2
6ske B 22 B 74
A redox-regulated disulphide may form within Adhesion G protein-coupled receptor L2 between cysteines 51 and 103 (22 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
6ske
Structure name
teneurin 2 in complex with latrophilin 2 lec domain
Structure deposition date
2019-08-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8JZZ7
Residue number A
51
Residue number B
103
Peptide name
Adhesion G protein-coupled receptor L2
Ligandability
Cysteine 51 of Adhesion G protein-coupled receptor L2
Cysteine 103 of Adhesion G protein-coupled receptor L2
If this tool was useful for finding a disulphide, please cite: