Persulfide dioxygenase ETHE1, mitochondrial

Intramolecular

A redox-regulated disulphide may form within Persulfide dioxygenase ETHE1, mitochondrial between cysteines 170 and 219. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4chl

Structure name

human ethylmalonic encephalopathy protein 1 (hethe1)

Structure deposition date

2013-12-03

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O95571

Residue number A

170

Residue number B

219

Peptide name

Persulfide dioxygenase ETHE1, mitochondrial

Ligandability

Cysteine 170 of Persulfide dioxygenase ETHE1, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 219 of Persulfide dioxygenase ETHE1, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Persulfide dioxygenase ETHE1, mitochondrial between cysteines 80 and 139. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?