CCR4-NOT transcription complex subunit 4
Intramolecular
Cysteine 14 and cysteine 38
Cysteine 38 and cysteine 41
Cysteine 31 and cysteine 33
Cysteine 14 and cysteine 41
Cysteine 14 and cysteine 17
Cysteine 33 and cysteine 56
Cysteine 53 and cysteine 56
Cysteine 33 and cysteine 53
Cysteine 31 and cysteine 53
Cysteine 17 and cysteine 38
More...Cysteine 31 and cysteine 56
Cysteine 17 and cysteine 41
1ur6 B 14 B 38
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 14 and 38.
Details
Redox score ?
87
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
62
Minimum pKa ?
5
% buried
56
Peptide accession
O95628
Residue number A
14
Residue number B
38
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 14 of CCR4-NOT transcription complex subunit 4
Cysteine 38 of CCR4-NOT transcription complex subunit 4
1ur6 B 38 B 41
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 38 and 41.
Details
Redox score ?
86
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
72
Minimum pKa ?
5
% buried
60
Peptide accession
O95628
Residue number A
38
Residue number B
41
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 38 of CCR4-NOT transcription complex subunit 4
Cysteine 41 of CCR4-NOT transcription complex subunit 4
1ur6 B 31 B 33
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 31 and 33.
Details
Redox score ?
86
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
40
Minimum pKa ?
8
% buried
2
Peptide accession
O95628
Residue number A
31
Residue number B
33
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 31 of CCR4-NOT transcription complex subunit 4
Cysteine 33 of CCR4-NOT transcription complex subunit 4
1ur6 B 14 B 41
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 14 and 41.
Details
Redox score ?
83
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
73
Minimum pKa ?
6
% buried
70
Peptide accession
O95628
Residue number A
14
Residue number B
41
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 14 of CCR4-NOT transcription complex subunit 4
Cysteine 41 of CCR4-NOT transcription complex subunit 4
1ur6 B 14 B 17
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 14 and 17.
Details
Redox score ?
83
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
68
Minimum pKa ?
6
% buried
70
Peptide accession
O95628
Residue number A
14
Residue number B
17
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 14 of CCR4-NOT transcription complex subunit 4
Cysteine 17 of CCR4-NOT transcription complex subunit 4
1ur6 B 33 B 56
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 33 and 56.
Details
Redox score ?
82
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
35
Minimum pKa ?
8
% buried
1
Peptide accession
O95628
Residue number A
33
Residue number B
56
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 33 of CCR4-NOT transcription complex subunit 4
Cysteine 56 of CCR4-NOT transcription complex subunit 4
1ur6 B 53 B 56
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 53 and 56.
Details
Redox score ?
81
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
53
Minimum pKa ?
8
% buried
15
Peptide accession
O95628
Residue number A
53
Residue number B
56
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 53 of CCR4-NOT transcription complex subunit 4
Cysteine 56 of CCR4-NOT transcription complex subunit 4
1ur6 B 33 B 53
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 33 and 53.
Details
Redox score ?
81
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
15
Peptide accession
O95628
Residue number A
33
Residue number B
53
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 33 of CCR4-NOT transcription complex subunit 4
Cysteine 53 of CCR4-NOT transcription complex subunit 4
1ur6 B 31 B 53
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 31 and 53.
Details
Redox score ?
80
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
58
Minimum pKa ?
9
% buried
16
Peptide accession
O95628
Residue number A
31
Residue number B
53
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 31 of CCR4-NOT transcription complex subunit 4
Cysteine 53 of CCR4-NOT transcription complex subunit 4
1ur6 B 17 B 38
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 17 and 38.
Details
Redox score ?
76
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
5
Half-sphere exposure sum ?
67
Minimum pKa ?
5
% buried
60
Peptide accession
O95628
Residue number A
17
Residue number B
38
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 17 of CCR4-NOT transcription complex subunit 4
Cysteine 38 of CCR4-NOT transcription complex subunit 4
1ur6 B 31 B 56
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 31 and 56.
Details
Redox score ?
75
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
5
Half-sphere exposure sum ?
43
Minimum pKa ?
8
% buried
2
Peptide accession
O95628
Residue number A
31
Residue number B
56
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 31 of CCR4-NOT transcription complex subunit 4
Cysteine 56 of CCR4-NOT transcription complex subunit 4
1ur6 B 17 B 41
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 4 between cysteines 17 and 41. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
1ur6
Structure name
nmr based structural model of the ubch5b-cnot4 complex
Structure deposition date
2003-10-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
77
Minimum pKa ?
18
% buried
74
Peptide accession
O95628
Residue number A
17
Residue number B
41
Peptide name
CCR4-NOT transcription complex subunit 4
Ligandability
Cysteine 17 of CCR4-NOT transcription complex subunit 4
Cysteine 41 of CCR4-NOT transcription complex subunit 4
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