Tetraspanin-15
Intramolecular
Cysteine 171 and cysteine 179
Cysteine 186 and cysteine 198
Cysteine 155 and cysteine 185
Cysteine 154 and cysteine 219
Cysteine 155 and cysteine 219
Cysteine 185 and cysteine 219
Cysteine 185 and cysteine 186
Cysteine 154 and cysteine 155
Cysteine 154 and cysteine 185
Cysteine 155 and cysteine 186
More...Cysteine 185 and cysteine 198
Cysteine 155 and cysteine 198
7rdb E 171 E 179
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 171 and 179.
Details
Redox score ?
83
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
171
Residue number B
179
Peptide name
Tetraspanin-15
Ligandability
Cysteine 171 of Tetraspanin-15
Cysteine 179 of Tetraspanin-15
7rdb X 186 X 198
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 186 and 198.
Details
Redox score ?
82
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
186
Residue number B
198
Peptide name
Tetraspanin-15
Ligandability
Cysteine 186 of Tetraspanin-15
Cysteine 198 of Tetraspanin-15
7rdb O 155 O 185
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 155 and 185.
Details
Redox score ?
79
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
155
Residue number B
185
Peptide name
Tetraspanin-15
Ligandability
Cysteine 155 of Tetraspanin-15
Cysteine 185 of Tetraspanin-15
7rd5 F 154 F 219
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 154 and 219.
Details
Redox score ?
78
PDB code
7rd5
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel) in complex with 1c12 fab
Structure deposition date
2021-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
154
Residue number B
219
Peptide name
Tetraspanin-15
Ligandability
Cysteine 154 of Tetraspanin-15
Cysteine 219 of Tetraspanin-15
7rd5 F 155 F 219
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 155 and 219. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
7rd5
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel) in complex with 1c12 fab
Structure deposition date
2021-07-09
Thiol separation (Å)
6
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
155
Residue number B
219
Peptide name
Tetraspanin-15
Ligandability
Cysteine 155 of Tetraspanin-15
Cysteine 219 of Tetraspanin-15
7rdb D 185 D 219
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 185 and 219. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
185
Residue number B
219
Peptide name
Tetraspanin-15
Ligandability
Cysteine 185 of Tetraspanin-15
Cysteine 219 of Tetraspanin-15
7rdb F 185 F 186
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 185 and 186. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
185
Residue number B
186
Peptide name
Tetraspanin-15
Ligandability
Cysteine 185 of Tetraspanin-15
Cysteine 186 of Tetraspanin-15
7rdb B 154 B 155
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 154 and 155. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
154
Residue number B
155
Peptide name
Tetraspanin-15
Ligandability
Cysteine 154 of Tetraspanin-15
Cysteine 155 of Tetraspanin-15
7rdb W 154 W 185
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 154 and 185. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
154
Residue number B
185
Peptide name
Tetraspanin-15
Ligandability
Cysteine 154 of Tetraspanin-15
Cysteine 185 of Tetraspanin-15
7rdb U 155 U 186
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 155 and 186. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
155
Residue number B
186
Peptide name
Tetraspanin-15
Ligandability
Cysteine 155 of Tetraspanin-15
Cysteine 186 of Tetraspanin-15
7rdb N 185 N 198
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 185 and 198. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
185
Residue number B
198
Peptide name
Tetraspanin-15
Ligandability
Cysteine 185 of Tetraspanin-15
Cysteine 198 of Tetraspanin-15
7rdb U 155 U 198
A redox-regulated disulphide may form within Tetraspanin-15 between cysteines 155 and 198. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
7rdb
Structure name
crystal structure of tspan15 large extracellular loop (tspan15 lel)
Structure deposition date
2021-07-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95858
Residue number A
155
Residue number B
198
Peptide name
Tetraspanin-15
Ligandability
Cysteine 155 of Tetraspanin-15
Cysteine 198 of Tetraspanin-15
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