a tool for identifying drug-targetable redox-active disulphides

Thioredoxin domain-containing protein 12

Intramolecular

Cysteine 66 and cysteine 69 L

A redox-regulated disulphide may form within Thioredoxin domain-containing protein 12 between cysteines 66 and 69.

Details

Redox score ?

77

PDB code

Structure name

endoplasmic reticulum protein rp19 o95881

Structure deposition date

2004-02-17

Thiol separation (Å)

4

Half-sphere exposure sum ?

50

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

66

Residue number B

69

Peptide name

Thioredoxin domain-containing protein 12

Ligandability

Cysteine 66 of Thioredoxin domain-containing protein 12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 69 of Thioredoxin domain-containing protein 12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

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