Reversion-inducing cysteine-rich protein with Kazal motifs
Intramolecular
Cysteine 225 and cysteine 250
Cysteine 217 and cysteine 229
Cysteine 216 and cysteine 263
Cysteine 229 and cysteine 250
Cysteine 225 and cysteine 229
Cysteine 217 and cysteine 250
Cysteine 216 and cysteine 229
Cysteine 217 and cysteine 225
Cysteine 216 and cysteine 217
Cysteine 229 and cysteine 263
Cysteine 217 and cysteine 263
6wbh A 392 A 417
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 225 and 250 (392 and 417 respectively in this structure).
Details
Redox score ?
85
PDB code
6wbh
Structure name
crystal structure of mreck(cc4) in fusion with engineered mbp at medium resolution
Structure deposition date
2020-03-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
225
Residue number B
250
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 225 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 250 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbh A 384 A 396
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 217 and 229 (384 and 396 respectively in this structure).
Details
Redox score ?
85
PDB code
6wbh
Structure name
crystal structure of mreck(cc4) in fusion with engineered mbp at medium resolution
Structure deposition date
2020-03-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
217
Residue number B
229
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 217 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 229 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbh A 383 A 430
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 216 and 263 (383 and 430 respectively in this structure).
Details
Redox score ?
83
PDB code
6wbh
Structure name
crystal structure of mreck(cc4) in fusion with engineered mbp at medium resolution
Structure deposition date
2020-03-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
216
Residue number B
263
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 216 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 263 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbj A 396 A 417
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 229 and 250 (396 and 417 respectively in this structure).
Details
Redox score ?
67
PDB code
6wbj
Structure name
high resolution crystal structure of mreck(cc4) in fusion with engineered mbp
Structure deposition date
2020-03-26
Thiol separation (Å)
5
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
229
Residue number B
250
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 229 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 250 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbj A 392 A 396
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 225 and 229 (392 and 396 respectively in this structure).
Details
Redox score ?
63
PDB code
6wbj
Structure name
high resolution crystal structure of mreck(cc4) in fusion with engineered mbp
Structure deposition date
2020-03-26
Thiol separation (Å)
6
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
225
Residue number B
229
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 225 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 229 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbh A 384 A 417
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 217 and 250 (384 and 417 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
6wbh
Structure name
crystal structure of mreck(cc4) in fusion with engineered mbp at medium resolution
Structure deposition date
2020-03-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
217
Residue number B
250
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 217 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 250 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbh A 383 A 396
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 216 and 229 (383 and 396 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
6wbh
Structure name
crystal structure of mreck(cc4) in fusion with engineered mbp at medium resolution
Structure deposition date
2020-03-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
216
Residue number B
229
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 216 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 229 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbj A 384 A 392
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 217 and 225 (384 and 392 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
6wbj
Structure name
high resolution crystal structure of mreck(cc4) in fusion with engineered mbp
Structure deposition date
2020-03-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
217
Residue number B
225
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 217 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 225 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbj A 383 A 384
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 216 and 217 (383 and 384 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
6wbj
Structure name
high resolution crystal structure of mreck(cc4) in fusion with engineered mbp
Structure deposition date
2020-03-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
216
Residue number B
217
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 216 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 217 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbj A 396 A 430
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 229 and 263 (396 and 430 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
6wbj
Structure name
high resolution crystal structure of mreck(cc4) in fusion with engineered mbp
Structure deposition date
2020-03-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
229
Residue number B
263
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 229 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 263 of Reversion-inducing cysteine-rich protein with Kazal motifs
6wbj A 384 A 430
A redox-regulated disulphide may form within Reversion-inducing cysteine-rich protein with Kazal motifs between cysteines 217 and 263 (384 and 430 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
6wbj
Structure name
high resolution crystal structure of mreck(cc4) in fusion with engineered mbp
Structure deposition date
2020-03-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Z0J1
Residue number A
217
Residue number B
263
Peptide name
Reversion-inducing cysteine-rich protein with Kazal motifs
Ligandability
Cysteine 217 of Reversion-inducing cysteine-rich protein with Kazal motifs
Cysteine 263 of Reversion-inducing cysteine-rich protein with Kazal motifs
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