Interleukin-18-binding protein
Intramolecular
Cysteine 64 and cysteine 89
Cysteine 86 and cysteine 150
Cysteine 86 and cysteine 131
Cysteine 131 and cysteine 150
Cysteine 89 and cysteine 131
7al7 A 64 A 89
A redox-regulated disulphide may form within Interleukin-18-binding protein between cysteines 64 and 89.
Details
Redox score ?
85
PDB code
7al7
Structure name
the crystal structure of human il-18 in complex with human il-18 binding protein
Structure deposition date
2020-10-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95998
Residue number A
64
Residue number B
89
Peptide name
Interleukin-18-binding protein
Ligandability
Cysteine 64 of Interleukin-18-binding protein
Cysteine 89 of Interleukin-18-binding protein
7al7 A 86 A 150
A redox-regulated disulphide may form within Interleukin-18-binding protein between cysteines 86 and 150.
Details
Redox score ?
81
PDB code
7al7
Structure name
the crystal structure of human il-18 in complex with human il-18 binding protein
Structure deposition date
2020-10-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
O95998
Residue number A
86
Residue number B
150
Peptide name
Interleukin-18-binding protein
Ligandability
Cysteine 86 of Interleukin-18-binding protein
Cysteine 150 of Interleukin-18-binding protein
7al7 A 86 A 131
A redox-regulated disulphide may form within Interleukin-18-binding protein between cysteines 86 and 131. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
7al7
Structure name
the crystal structure of human il-18 in complex with human il-18 binding protein
Structure deposition date
2020-10-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
10
% buried
nan
Peptide accession
O95998
Residue number A
86
Residue number B
131
Peptide name
Interleukin-18-binding protein
Ligandability
Cysteine 86 of Interleukin-18-binding protein
Cysteine 131 of Interleukin-18-binding protein
7al7 A 131 A 150
A redox-regulated disulphide may form within Interleukin-18-binding protein between cysteines 131 and 150. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
33
PDB code
7al7
Structure name
the crystal structure of human il-18 in complex with human il-18 binding protein
Structure deposition date
2020-10-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
10
% buried
nan
Peptide accession
O95998
Residue number A
131
Residue number B
150
Peptide name
Interleukin-18-binding protein
Ligandability
Cysteine 131 of Interleukin-18-binding protein
Cysteine 150 of Interleukin-18-binding protein
7al7 A 89 A 131
A redox-regulated disulphide may form within Interleukin-18-binding protein between cysteines 89 and 131. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
30
PDB code
7al7
Structure name
the crystal structure of human il-18 in complex with human il-18 binding protein
Structure deposition date
2020-10-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
nan
Peptide accession
O95998
Residue number A
89
Residue number B
131
Peptide name
Interleukin-18-binding protein
Ligandability
Cysteine 89 of Interleukin-18-binding protein
Cysteine 131 of Interleukin-18-binding protein
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