ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Cytochrome c oxidase subunit 1

Intramolecular
Cysteine 196 and cysteine 200
A redox-regulated disulphide may form within Cytochrome c oxidase subunit 1 between cysteines 196 and 200.

Details

Redox score ?
nan
PDB code
7xma
Structure name
crystal structure of bovine heart cytochrome c oxidase, apo structure with dmso
Structure deposition date
2022-04-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
94
Minimum pKa ?
2
% buried
100
Peptide accession
Q6EMS9
Residue number A
196
Residue number B
200
Peptide name
Cytochrome c oxidase subunit 1

Ligandability

Cysteine 196 of Cytochrome c oxidase subunit 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 200 of Cytochrome c oxidase subunit 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 196 in protein A could not be asigned to a Uniprot residue.
Cysteine 200 in protein B could not be asigned to a Uniprot residue.
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