a tool for identifying drug-targetable redox-active disulphides

Cytochrome c oxidase subunit 2

Intramolecular

Cysteine 196 and cysteine 200

A redox-regulated disulphide may form within Cytochrome c oxidase subunit 2 between cysteines 196 and 200.

Details

Redox score ?

65

PDB code

Structure name

electron transfer complex of cytochrome c and cytochrome c oxidase at 2

Structure deposition date

2016-03-24

Thiol separation (Å)

3

Half-sphere exposure sum ?

97

Minimum pK_a ?

13

% buried

nan

Peptide accession

Residue number A

196

Residue number B

200

Peptide name

Cytochrome c oxidase subunit 2

Ligandability

Cysteine 196 of Cytochrome c oxidase subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 200 of Cytochrome c oxidase subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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