Purine nucleoside phosphorylase

Intramolecular

A redox-regulated disulphide may form within Purine nucleoside phosphorylase between cysteines 31 and 78. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4gka

Structure name

crystal structure of purine nucleoside phosphorylase (w16y, w94y, w178y, h257w) mutant from human complexed with phosphate

Structure deposition date

2012-08-10

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P00491

Residue number A

Residue number B

Peptide name

Purine nucleoside phosphorylase

Ligandability

Cysteine 31 of Purine nucleoside phosphorylase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.