Oxytocin-neurophysin 1
Intermolecular
Cysteine 110 and cysteine 110
Intramolecular
Cysteine 20 and cysteine 25
Cysteine 41 and cysteine 85
Cysteine 98 and cysteine 116
Cysteine 52 and cysteine 75
Cysteine 92 and cysteine 116
Cysteine 92 and cysteine 104
Cysteine 44 and cysteine 58
Cysteine 59 and cysteine 65
Cysteine 92 and cysteine 98
More...Cysteine 44 and cysteine 75
Cysteine 59 and cysteine 105
Cysteine 44 and cysteine 52
Cysteine 65 and cysteine 105
Cysteine 104 and cysteine 116
Cysteine 59 and cysteine 110
Cysteine 65 and cysteine 110
Cysteine 58 and cysteine 75
Cysteine 52 and cysteine 58
Cysteine 41 and cysteine 52
Cysteine 98 and cysteine 104
Cysteine 58 and cysteine 59
Cysteine 105 and cysteine 116
Cysteine 52 and cysteine 85
Cysteine 41 and cysteine 75
Cysteine 75 and cysteine 85
Cysteine 44 and cysteine 59
Cysteine 59 and cysteine 85
Cysteine 65 and cysteine 116
Cysteine 92 and cysteine 105
Cysteine 41 and cysteine 44
Cysteine 85 and cysteine 105
Cysteine 92 and cysteine 110
Cysteine 104 and cysteine 110
Cysteine 59 and cysteine 75
Cysteine 75 and cysteine 105
Cysteine 85 and cysteine 110
Cysteine 52 and cysteine 105
Cysteine 44 and cysteine 85
Cysteine 110 and cysteine 116
2hnw C 79 D 79
A redox-regulated disulphide may form between two units of Oxytocin-neurophysin 1 at cysteines 110 and 110 (79 and 79 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
94
Minimum pKa ?
nan
% buried
nan
Peptide A name
Oxytocin-neurophysin 1
Peptide B name
Oxytocin-neurophysin 1
Peptide A accession
P01175
Peptide B accession
P01175
Peptide A residue number
110
Peptide B residue number
110
Ligandability
7ofg A 1 A 6
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 20 and 25 (1 and 6 respectively in this structure).
Details
Redox score ?
92
PDB code
7ofg
Structure name
oxytocin nmr solution structure
Structure deposition date
2021-05-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01178
Residue number A
20
Residue number B
25
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 20 of Oxytocin-neurophysin 1
Cysteine 25 of Oxytocin-neurophysin 1
2hnw B 10 B 54
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 41 and 85 (10 and 54 respectively in this structure).
Details
Redox score ?
83
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
13
Peptide accession
P01175
Residue number A
41
Residue number B
85
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 41 of Oxytocin-neurophysin 1
Cysteine 85 of Oxytocin-neurophysin 1
2hnv D 67 D 85
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 98 and 116 (67 and 85 respectively in this structure).
Details
Redox score ?
83
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
98
Residue number B
116
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 98 of Oxytocin-neurophysin 1
Cysteine 116 of Oxytocin-neurophysin 1
2hnv D 21 D 44
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 52 and 75 (21 and 44 respectively in this structure).
Details
Redox score ?
81
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
52
Residue number B
75
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 52 of Oxytocin-neurophysin 1
Cysteine 75 of Oxytocin-neurophysin 1
2hnu C 61 C 85
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 92 and 116 (61 and 85 respectively in this structure).
Details
Redox score ?
79
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
92
Residue number B
116
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 92 of Oxytocin-neurophysin 1
Cysteine 116 of Oxytocin-neurophysin 1
2hnw B 61 B 73
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 92 and 104 (61 and 73 respectively in this structure).
Details
Redox score ?
78
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
64
Minimum pKa ?
9
% buried
14
Peptide accession
P01175
Residue number A
92
Residue number B
104
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 92 of Oxytocin-neurophysin 1
Cysteine 104 of Oxytocin-neurophysin 1
2hnv D 13 D 27
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 44 and 58 (13 and 27 respectively in this structure).
Details
Redox score ?
78
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
44
Residue number B
58
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 44 of Oxytocin-neurophysin 1
Cysteine 58 of Oxytocin-neurophysin 1
2hnu C 28 C 34
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 59 and 65 (28 and 34 respectively in this structure).
Details
Redox score ?
77
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
101
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
59
Residue number B
65
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 59 of Oxytocin-neurophysin 1
Cysteine 65 of Oxytocin-neurophysin 1
2hnw B 61 B 67
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 92 and 98 (61 and 67 respectively in this structure).
Details
Redox score ?
76
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
62
Minimum pKa ?
9
% buried
nan
Peptide accession
P01175
Residue number A
92
Residue number B
98
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 92 of Oxytocin-neurophysin 1
Cysteine 98 of Oxytocin-neurophysin 1
2hnw B 13 B 44
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 44 and 75 (13 and 44 respectively in this structure).
Details
Redox score ?
75
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
44
Residue number B
75
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 44 of Oxytocin-neurophysin 1
Cysteine 75 of Oxytocin-neurophysin 1
2hnw E 28 E 74
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 59 and 105 (28 and 74 respectively in this structure).
Details
Redox score ?
75
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
59
Residue number B
105
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 59 of Oxytocin-neurophysin 1
Cysteine 105 of Oxytocin-neurophysin 1
2hnw D 13 D 21
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 44 and 52 (13 and 21 respectively in this structure).
Details
Redox score ?
73
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
44
Residue number B
52
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 44 of Oxytocin-neurophysin 1
Cysteine 52 of Oxytocin-neurophysin 1
2hnw D 34 D 74
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 65 and 105 (34 and 74 respectively in this structure).
Details
Redox score ?
71
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
99
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
65
Residue number B
105
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 65 of Oxytocin-neurophysin 1
Cysteine 105 of Oxytocin-neurophysin 1
2hnu A 73 A 85
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 104 and 116 (73 and 85 respectively in this structure).
Details
Redox score ?
68
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
104
Residue number B
116
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 104 of Oxytocin-neurophysin 1
Cysteine 116 of Oxytocin-neurophysin 1
2hnu D 28 D 79
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 59 and 110 (28 and 79 respectively in this structure).
Details
Redox score ?
67
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
98
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
59
Residue number B
110
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 59 of Oxytocin-neurophysin 1
Cysteine 110 of Oxytocin-neurophysin 1
2hnv C 34 C 79
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 65 and 110 (34 and 79 respectively in this structure).
Details
Redox score ?
66
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
103
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
65
Residue number B
110
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 65 of Oxytocin-neurophysin 1
Cysteine 110 of Oxytocin-neurophysin 1
2hnw E 27 E 44
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 58 and 75 (27 and 44 respectively in this structure).
Details
Redox score ?
61
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
58
Residue number B
75
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 58 of Oxytocin-neurophysin 1
Cysteine 75 of Oxytocin-neurophysin 1
2hnw D 21 D 27
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 52 and 58 (21 and 27 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
97
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
52
Residue number B
58
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 52 of Oxytocin-neurophysin 1
Cysteine 58 of Oxytocin-neurophysin 1
2hnv D 10 D 21
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 41 and 52 (10 and 21 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
41
Residue number B
52
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 41 of Oxytocin-neurophysin 1
Cysteine 52 of Oxytocin-neurophysin 1
2hnv B 67 B 73
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 98 and 104 (67 and 73 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
98
Residue number B
104
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 98 of Oxytocin-neurophysin 1
Cysteine 104 of Oxytocin-neurophysin 1
2hnw B 27 B 28
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 58 and 59 (27 and 28 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
106
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
58
Residue number B
59
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 58 of Oxytocin-neurophysin 1
Cysteine 59 of Oxytocin-neurophysin 1
2hnu A 74 A 85
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 105 and 116 (74 and 85 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
105
Residue number B
116
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 105 of Oxytocin-neurophysin 1
Cysteine 116 of Oxytocin-neurophysin 1
2hnv A 21 A 54
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 52 and 85 (21 and 54 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
52
Residue number B
85
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 52 of Oxytocin-neurophysin 1
Cysteine 85 of Oxytocin-neurophysin 1
2hnu E 10 E 44
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 41 and 75 (10 and 44 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
41
Residue number B
75
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 41 of Oxytocin-neurophysin 1
Cysteine 75 of Oxytocin-neurophysin 1
2hnu D 44 D 54
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 75 and 85 (44 and 54 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
75
Residue number B
85
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 75 of Oxytocin-neurophysin 1
Cysteine 85 of Oxytocin-neurophysin 1
2hnv D 13 D 28
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 44 and 59 (13 and 28 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
44
Residue number B
59
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 44 of Oxytocin-neurophysin 1
Cysteine 59 of Oxytocin-neurophysin 1
2lbh A 28 A 54
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 59 and 85 (28 and 54 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
2lbh
Structure name
solution structure of the dimeric form of a unliganded bovine neurophysin, minimized average structure
Structure deposition date
2011-03-31
Thiol separation (Å)
8
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
59
Residue number B
85
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 59 of Oxytocin-neurophysin 1
Cysteine 85 of Oxytocin-neurophysin 1
2hnu E 34 E 85
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 65 and 116 (34 and 85 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
65
Residue number B
116
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 65 of Oxytocin-neurophysin 1
Cysteine 116 of Oxytocin-neurophysin 1
2hnw B 61 B 74
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 92 and 105 (61 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
9
% buried
nan
Peptide accession
P01175
Residue number A
92
Residue number B
105
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 92 of Oxytocin-neurophysin 1
Cysteine 105 of Oxytocin-neurophysin 1
2hnv D 10 D 13
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 41 and 44 (10 and 13 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
41
Residue number B
44
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 41 of Oxytocin-neurophysin 1
Cysteine 44 of Oxytocin-neurophysin 1
1l5c A 54 A 74
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 85 and 105 (54 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
1l5c
Structure name
solution structure of the monomeric form of a mutant unliganded bovine neurophysin, 20 structures
Structure deposition date
2002-03-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
85
Residue number B
105
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 85 of Oxytocin-neurophysin 1
Cysteine 105 of Oxytocin-neurophysin 1
2hnw A 61 A 79
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 92 and 110 (61 and 79 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
92
Residue number B
110
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 92 of Oxytocin-neurophysin 1
Cysteine 110 of Oxytocin-neurophysin 1
2hnv D 73 D 79
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 104 and 110 (73 and 79 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
94
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
104
Residue number B
110
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 104 of Oxytocin-neurophysin 1
Cysteine 110 of Oxytocin-neurophysin 1
2hnv D 28 D 44
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 59 and 75 (28 and 44 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2hnv
Structure name
crystal structure of a dipeptide complex of the q58v mutant of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
87
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
59
Residue number B
75
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 59 of Oxytocin-neurophysin 1
Cysteine 75 of Oxytocin-neurophysin 1
2lbh A 44 A 74
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 75 and 105 (44 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
2lbh
Structure name
solution structure of the dimeric form of a unliganded bovine neurophysin, minimized average structure
Structure deposition date
2011-03-31
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
75
Residue number B
105
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 75 of Oxytocin-neurophysin 1
Cysteine 105 of Oxytocin-neurophysin 1
1l5c A 54 A 79
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 85 and 110 (54 and 79 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
1l5c
Structure name
solution structure of the monomeric form of a mutant unliganded bovine neurophysin, 20 structures
Structure deposition date
2002-03-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
85
Residue number B
110
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 85 of Oxytocin-neurophysin 1
Cysteine 110 of Oxytocin-neurophysin 1
1l5c A 21 A 74
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 52 and 105 (21 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
1l5c
Structure name
solution structure of the monomeric form of a mutant unliganded bovine neurophysin, 20 structures
Structure deposition date
2002-03-06
Thiol separation (Å)
8
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
52
Residue number B
105
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 52 of Oxytocin-neurophysin 1
Cysteine 105 of Oxytocin-neurophysin 1
2hnw C 13 C 54
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 44 and 85 (13 and 54 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
2hnw
Structure name
crystal structure of the f91stop mutant of des1-6 bovine neurophysin- i, unliganded state
Structure deposition date
2006-07-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
44
Residue number B
85
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 44 of Oxytocin-neurophysin 1
Cysteine 85 of Oxytocin-neurophysin 1
2hnu B 79 B 85
A redox-regulated disulphide may form within Oxytocin-neurophysin 1 between cysteines 110 and 116 (79 and 85 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2hnu
Structure name
crystal structure of a dipeptide complex of bovine neurophysin-i
Structure deposition date
2006-07-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01175
Residue number A
110
Residue number B
116
Peptide name
Oxytocin-neurophysin 1
Ligandability
Cysteine 110 of Oxytocin-neurophysin 1
Cysteine 116 of Oxytocin-neurophysin 1
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