ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Immunoglobulin kappa variable 1-33

Intramolecular
Cysteine 45 and cysteine 110
A redox-regulated disulphide may form within Immunoglobulin kappa variable 1-33 between cysteines 45 and 110 (23 and 88 respectively in this structure).

Details

Redox score ?
81
PDB code
2q20
Structure name
structure of the germline vk1 o18/o8 light chain variable domain homodimer
Structure deposition date
2007-05-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
92
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01594
Residue number A
45
Residue number B
110
Peptide name
Immunoglobulin kappa variable 1-33

Ligandability

Cysteine 45 of Immunoglobulin kappa variable 1-33

Cysteine 110 of Immunoglobulin kappa variable 1-33

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