T cell receptor alpha chain constant
Intermolecular
Cysteine 94 and cysteine 131 of T cell receptor beta constant 2
Cysteine 157 and cysteine 176 of Human nkt tcr beta chain
Intramolecular
Cysteine 22 and cysteine 72
Cysteine 22 and cysteine 90
Cysteine 23 and cysteine 104
Cysteine 21 and cysteine 87
6jxr m 227 n 264
A redox-regulated disulphide may form between cysteine 94 of T cell receptor alpha chain constant and cysteine 131 of T cell receptor beta constant 2 (227 and 264 respectively in this structure).
Details
Redox score ?
85
PDB code
6jxr
Structure name
structure of human t cell receptor-cd3 complex
Structure deposition date
2019-04-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
43
Minimum pKa ?
nan
% buried
nan
Peptide A name
T cell receptor alpha chain constant
Peptide B name
T cell receptor beta constant 2
Peptide A accession
P01848
Peptide B accession
A0A0G2JMB4
Peptide A residue number
94
Peptide B residue number
131
Ligandability
Cysteine 94 of T cell receptor alpha chain constant
Cysteine 131 of T cell receptor beta constant 2
6dkp D 157 E 172
A redox-regulated disulphide may form between cysteine 157 of T cell receptor alpha chain constant and cysteine 176 of Human nkt tcr beta chain (157 and 172 respectively in this structure).
Details
Redox score ?
80
PDB code
6dkp
Structure name
the complex among dmf5(alpha-d26y, alpha-y50a,beta-l98w) tcr, human class i mhc hla-a2 and mart-1(26-35)(a27l) peptide
Structure deposition date
2018-05-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide A name
T cell receptor alpha chain constant
Peptide B name
Human nkt tcr beta chain
Peptide A accession
P01848
Peptide B accession
K7N5M4
Peptide A residue number
157
Peptide B residue number
176
Ligandability
Cysteine 157 of T cell receptor alpha chain constant
Cysteine 176 of Human nkt tcr beta chain
Cysteine 157 in protein A could not be asigned to a Uniprot residue.
6dkp D 132 D 182
A redox-regulated disulphide may form within T cell receptor alpha chain constant between cysteines 22 and 72 (132 and 182 respectively in this structure).
Details
Redox score ?
79
PDB code
6dkp
Structure name
the complex among dmf5(alpha-d26y, alpha-y50a,beta-l98w) tcr, human class i mhc hla-a2 and mart-1(26-35)(a27l) peptide
Structure deposition date
2018-05-30
Thiol separation (Å)
3
Half-sphere exposure sum ?
69
Minimum pKa ?
7
% buried
58
Peptide accession
P01848
Residue number A
22
Residue number B
72
Peptide name
T cell receptor alpha chain constant
Ligandability
Cysteine 22 of T cell receptor alpha chain constant
Cysteine 72 of T cell receptor alpha chain constant
2bnu A 23 A 90
A redox-regulated disulphide may form within T cell receptor alpha chain constant between cysteines 22 and 90 (23 and 90 respectively in this structure).
Details
Redox score ?
nan
PDB code
2bnu
Structure name
structural and kinetic basis for heightened immunogenicity of t cell vaccines
Structure deposition date
2005-04-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01848
Residue number A
22
Residue number B
90
Peptide name
T cell receptor alpha chain constant
Ligandability
Cysteine 22 of T cell receptor alpha chain constant
Cysteine 90 of T cell receptor alpha chain constant
Cysteine 90 in protein B could not be asigned to a Uniprot residue.
7t2b N 23 N 104
A redox-regulated disulphide may form within T cell receptor alpha chain constant between cysteines 23 and 104.
Details
Redox score ?
nan
PDB code
7t2b
Structure name
crystal structure of the 5f tcr in complex with hla-dp4-ply
Structure deposition date
2021-12-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01848
Residue number A
23
Residue number B
104
Peptide name
T cell receptor alpha chain constant
Ligandability
Cysteine 23 of T cell receptor alpha chain constant
Cysteine 104 of T cell receptor alpha chain constant
Cysteine 23 in protein A could not be asigned to a Uniprot residue.
Cysteine 104 in protein B could not be asigned to a Uniprot residue.
3o6f C 21 C 87
A redox-regulated disulphide may form within T cell receptor alpha chain constant between cysteines 21 and 87.
Details
Redox score ?
nan
PDB code
3o6f
Structure name
crystal structure of a human autoimmune tcr ms2-3c8 bound to mhc class ii self-ligand mbp/hla-dr4
Structure deposition date
2010-07-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01848
Residue number A
21
Residue number B
87
Peptide name
T cell receptor alpha chain constant
Ligandability
Cysteine 21 of T cell receptor alpha chain constant
Cysteine 87 of T cell receptor alpha chain constant
Cysteine 21 in protein A could not be asigned to a Uniprot residue.
Cysteine 87 in protein B could not be asigned to a Uniprot residue.
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