ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Albumin

Intermolecular
Cysteine 582 and cysteine 582
Intramolecular
Cysteine 58 and cysteine 2301
Cysteine 114 and cysteine 125
Cysteine 77 and cysteine 392
Cysteine 582 and cysteine 567
Cysteine 77 and cysteine 86
Cysteine 339 and cysteine 276
Cysteine 192 and cysteine 201
Cysteine 302 and cysteine 313
Cysteine 289 and cysteine 303
More...
Cysteine 148 and cysteine 193
Cysteine 384 and cysteine 393
Cysteine 416 and cysteine 462
Cysteine 340 and cysteine 385
Cysteine 99 and cysteine 115
Cysteine 461 and cysteine 472
Cysteine 269 and cysteine 277
Cysteine 582 and cysteine 591
Cysteine 224 and cysteine 270
Cysteine 500 and cysteine 511
Cysteine 485 and cysteine 501
Cysteine 538 and cysteine 583
Cysteine 115 and cysteine 115
Cysteine 302 and cysteine 303
Cysteine 77 and cysteine 276
Cysteine 383 and cysteine 384
Cysteine 339 and cysteine 77
Cysteine 192 and cysteine 193
Cysteine 461 and cysteine 462
Cysteine 583 and cysteine 567
Cysteine 499 and cysteine 500
Cysteine 269 and cysteine 270
Cysteine 289 and cysteine 302
Cysteine 538 and cysteine 567
Cysteine 99 and cysteine 114
Cysteine 303 and cysteine 313
Cysteine 501 and cysteine 511
Cysteine 385 and cysteine 393
Cysteine 289 and cysteine 313
Cysteine 224 and cysteine 269
A redox-regulated disulphide may form between two units of Albumin at cysteines 582 and 582 (558 and 558 respectively in this structure).

Details

Redox score ?
64
PDB code
6qs9
Structure name
bovine serum albumin in complex with ketoprofen
Structure deposition date
2019-02-20
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide A name
Albumin
Peptide B name
Albumin
Peptide A accession
P02769
Peptide B accession
P02769
Peptide A residue number
582
Peptide B residue number
582

Ligandability

A redox-regulated disulphide may form within Albumin between cysteines 58 and 2301 (34 and 2301 respectively in this structure).

Details

Redox score ?
90
PDB code
7jwn
Structure name
crystal structure of human serum albumin in complex with ketoprofen
Structure deposition date
2020-08-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
58
Residue number B
2301
Peptide name
Albumin

Ligandability

Cysteine 58 of Albumin

Cysteine 2301 of Albumin

Cysteine 2301 in protein B could not be asigned to a Uniprot residue.
A redox-regulated disulphide may form within Albumin between cysteines 114 and 125 (90 and 101 respectively in this structure).

Details

Redox score ?
90
PDB code
3jqz
Structure name
crystal structure of human serum albumin complexed with lidocaine
Structure deposition date
2009-09-08
Thiol separation (Å)
3
Half-sphere exposure sum ?
61
Minimum pKa ?
4
% buried
57
Peptide accession
P02768
Residue number A
114
Residue number B
125
Peptide name
Albumin

Ligandability

Cysteine 114 of Albumin

Cysteine 125 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 77 and 392 (359 and 368 respectively in this structure).

Details

Redox score ?
89
PDB code
6qs9
Structure name
bovine serum albumin in complex with ketoprofen
Structure deposition date
2019-02-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02769
Residue number A
77
Residue number B
392
Peptide name
Albumin

Ligandability

Cysteine 77 of Albumin

Cysteine 392 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 582 and 567 (558 and 567 respectively in this structure).

Details

Redox score ?
88
PDB code
6a7p
Structure name
human serum albumin complexed with aripiprazole
Structure deposition date
2018-07-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
582
Residue number B
567
Peptide name
Albumin

Ligandability

Cysteine 582 of Albumin

Cysteine 567 of Albumin

Cysteine 567 in protein B could not be asigned to a Uniprot residue.
A redox-regulated disulphide may form within Albumin between cysteines 77 and 86 (53 and 62 respectively in this structure).

Details

Redox score ?
87
PDB code
3lu8
Structure name
human serum albumin in complex with compound 3
Structure deposition date
2010-02-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
77
Residue number B
86
Peptide name
Albumin

Ligandability

Cysteine 77 of Albumin

Cysteine 86 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 339 and 276 (315 and 360 respectively in this structure).

Details

Redox score ?
87
PDB code
6qs9
Structure name
bovine serum albumin in complex with ketoprofen
Structure deposition date
2019-02-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02769
Residue number A
339
Residue number B
276
Peptide name
Albumin

Ligandability

Cysteine 339 of Albumin

Cysteine 276 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 192 and 201 (168 and 177 respectively in this structure).

Details

Redox score ?
85
PDB code
6je7
Structure name
crystal structure of human serum albumin crystallized by ammonium sulfate
Structure deposition date
2019-02-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
192
Residue number B
201
Peptide name
Albumin

Ligandability

Cysteine 192 of Albumin

Cysteine 201 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 302 and 313 (278 and 289 respectively in this structure).

Details

Redox score ?
84
PDB code
4iw2
Structure name
hsa-glucose complex
Structure deposition date
2013-01-23
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
302
Residue number B
313
Peptide name
Albumin

Ligandability

Cysteine 302 of Albumin

Cysteine 313 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 289 and 303 (265 and 279 respectively in this structure).

Details

Redox score ?
84
PDB code
3lu6
Structure name
human serum albumin in complex with compound 1
Structure deposition date
2010-02-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
289
Residue number B
303
Peptide name
Albumin

Ligandability

Cysteine 289 of Albumin

Cysteine 303 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 148 and 193 (124 and 169 respectively in this structure).

Details

Redox score ?
84
PDB code
2bxg
Structure name
human serum albumin complexed with ibuprofen
Structure deposition date
2005-07-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
148
Residue number B
193
Peptide name
Albumin

Ligandability

Cysteine 148 of Albumin

Cysteine 193 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 384 and 393 (360 and 369 respectively in this structure).

Details

Redox score ?
84
PDB code
1n5u
Structure name
x-ray study of human serum albumin complexed with heme
Structure deposition date
2002-11-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
384
Residue number B
393
Peptide name
Albumin

Ligandability

Cysteine 384 of Albumin

Cysteine 393 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 416 and 462 (392 and 438 respectively in this structure).

Details

Redox score ?
83
PDB code
4k2c
Structure name
hsa ligand free
Structure deposition date
2013-04-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
416
Residue number B
462
Peptide name
Albumin

Ligandability

Cysteine 416 of Albumin

Cysteine 462 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 340 and 385 (316 and 361 respectively in this structure).

Details

Redox score ?
83
PDB code
2vuf
Structure name
human serum albumin complexed with fusidic acid
Structure deposition date
2008-05-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
340
Residue number B
385
Peptide name
Albumin

Ligandability

Cysteine 340 of Albumin

Cysteine 385 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 99 and 115 (75 and 91 respectively in this structure).

Details

Redox score ?
83
PDB code
5ije
Structure name
crystal structure of equine serum albumin in the presence of 30 mm zinc at ph 7
Structure deposition date
2016-03-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P35747
Residue number A
99
Residue number B
115
Peptide name
Albumin

Ligandability

Cysteine 99 of Albumin

Cysteine 115 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 461 and 472 (437 and 448 respectively in this structure).

Details

Redox score ?
83
PDB code
7ov6
Structure name
structure of human serum albumin in complex with aristolochic acid i at 1
Structure deposition date
2021-06-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
461
Residue number B
472
Peptide name
Albumin

Ligandability

Cysteine 461 of Albumin

Cysteine 472 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 269 and 277 (245 and 253 respectively in this structure).

Details

Redox score ?
83
PDB code
3lu7
Structure name
human serum albumin in complex with compound 2
Structure deposition date
2010-02-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
269
Residue number B
277
Peptide name
Albumin

Ligandability

Cysteine 269 of Albumin

Cysteine 277 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 582 and 591 (558 and 567 respectively in this structure).

Details

Redox score ?
81
PDB code
6m5e
Structure name
human serum albumin with cyclic peptide dalbavancin
Structure deposition date
2020-03-10
Thiol separation (Å)
3
Half-sphere exposure sum ?
49
Minimum pKa ?
9
% buried
0
Peptide accession
P02768
Residue number A
582
Residue number B
591
Peptide name
Albumin

Ligandability

Cysteine 582 of Albumin

Cysteine 591 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 224 and 270 (200 and 246 respectively in this structure).

Details

Redox score ?
79
PDB code
2bxf
Structure name
human serum albumin complexed with diazepam
Structure deposition date
2005-07-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
224
Residue number B
270
Peptide name
Albumin

Ligandability

Cysteine 224 of Albumin

Cysteine 270 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 500 and 511 (476 and 487 respectively in this structure).

Details

Redox score ?
78
PDB code
8ey5
Structure name
human serum albumin with cobalt (ii) and myristic acid - crystal 3
Structure deposition date
2022-10-26
Thiol separation (Å)
3
Half-sphere exposure sum ?
48
Minimum pKa ?
11
% buried
43
Peptide accession
P02768
Residue number A
500
Residue number B
511
Peptide name
Albumin

Ligandability

Cysteine 500 of Albumin

Cysteine 511 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 485 and 501 (461 and 477 respectively in this structure).

Details

Redox score ?
75
PDB code
5x52
Structure name
human serum albumin complexed with octanoate and n-acetyl-l-methionine
Structure deposition date
2017-02-14
Thiol separation (Å)
3
Half-sphere exposure sum ?
77
Minimum pKa ?
8
% buried
87
Peptide accession
P02768
Residue number A
485
Residue number B
501
Peptide name
Albumin

Ligandability

Cysteine 485 of Albumin

Cysteine 501 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 538 and 583 (514 and 559 respectively in this structure).

Details

Redox score ?
68
PDB code
8ey5
Structure name
human serum albumin with cobalt (ii) and myristic acid - crystal 3
Structure deposition date
2022-10-26
Thiol separation (Å)
5
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
8
Peptide accession
P02768
Residue number A
538
Residue number B
583
Peptide name
Albumin

Ligandability

Cysteine 538 of Albumin

Cysteine 583 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 115 and 115 (90 and 91 respectively in this structure).

Details

Redox score ?
66
PDB code
7djn
Structure name
human serum albumin
Structure deposition date
2020-11-20
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
115
Residue number B
115
Peptide name
Albumin

Ligandability

Cysteine 115 of Albumin

Cysteine 115 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 302 and 303 (278 and 279 respectively in this structure).

Details

Redox score ?
61
PDB code
1ao6
Structure name
crystal structure of human serum albumin
Structure deposition date
1997-07-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
302
Residue number B
303
Peptide name
Albumin

Ligandability

Cysteine 302 of Albumin

Cysteine 303 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 77 and 276 (359 and 360 respectively in this structure).

Details

Redox score ?
60
PDB code
6qs9
Structure name
bovine serum albumin in complex with ketoprofen
Structure deposition date
2019-02-20
Thiol separation (Å)
7
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02769
Residue number A
77
Residue number B
276
Peptide name
Albumin

Ligandability

Cysteine 77 of Albumin

Cysteine 276 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 383 and 384 (359 and 360 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
4j2v
Structure name
crystal structure of equine serum albumin in complex with 3,5- diiodosalicylic acid
Structure deposition date
2013-02-05
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P35747
Residue number A
383
Residue number B
384
Peptide name
Albumin

Ligandability

Cysteine 383 of Albumin

Cysteine 384 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 339 and 77 (315 and 359 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
6qs9
Structure name
bovine serum albumin in complex with ketoprofen
Structure deposition date
2019-02-20
Thiol separation (Å)
7
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02769
Residue number A
339
Residue number B
77
Peptide name
Albumin

Ligandability

Cysteine 339 of Albumin

Cysteine 77 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 192 and 193 (168 and 169 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
3v09
Structure name
crystal structure of rabbit serum albumin
Structure deposition date
2011-12-07
Thiol separation (Å)
7
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49065
Residue number A
192
Residue number B
193
Peptide name
Albumin

Ligandability

Cysteine 192 of Albumin

Cysteine 193 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 461 and 462 (437 and 438 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
57
PDB code
3v09
Structure name
crystal structure of rabbit serum albumin
Structure deposition date
2011-12-07
Thiol separation (Å)
7
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49065
Residue number A
461
Residue number B
462
Peptide name
Albumin

Ligandability

Cysteine 461 of Albumin

Cysteine 462 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 583 and 567 (559 and 567 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
55
PDB code
6a7p
Structure name
human serum albumin complexed with aripiprazole
Structure deposition date
2018-07-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
583
Residue number B
567
Peptide name
Albumin

Ligandability

Cysteine 583 of Albumin

Cysteine 567 of Albumin

Cysteine 567 in protein B could not be asigned to a Uniprot residue.
A redox-regulated disulphide may form within Albumin between cysteines 499 and 500 (475 and 476 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
55
PDB code
5orf
Structure name
structure of ovine serum albumin in p1 space group
Structure deposition date
2017-08-16
Thiol separation (Å)
7
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P14639
Residue number A
499
Residue number B
500
Peptide name
Albumin

Ligandability

Cysteine 499 of Albumin

Cysteine 500 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 269 and 270 (245 and 246 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
1ao6
Structure name
crystal structure of human serum albumin
Structure deposition date
1997-07-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
269
Residue number B
270
Peptide name
Albumin

Ligandability

Cysteine 269 of Albumin

Cysteine 270 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 289 and 302 (265 and 278 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
51
PDB code
8ey5
Structure name
human serum albumin with cobalt (ii) and myristic acid - crystal 3
Structure deposition date
2022-10-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
56
Minimum pKa ?
9
% buried
31
Peptide accession
P02768
Residue number A
289
Residue number B
302
Peptide name
Albumin

Ligandability

Cysteine 289 of Albumin

Cysteine 302 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 538 and 567 (514 and 567 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
49
PDB code
6a7p
Structure name
human serum albumin complexed with aripiprazole
Structure deposition date
2018-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
538
Residue number B
567
Peptide name
Albumin

Ligandability

Cysteine 538 of Albumin

Cysteine 567 of Albumin

Cysteine 567 in protein B could not be asigned to a Uniprot residue.
A redox-regulated disulphide may form within Albumin between cysteines 99 and 114 (75 and 90 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
5vnw
Structure name
crystal structure of nb
Structure deposition date
2017-05-01
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
99
Residue number B
114
Peptide name
Albumin

Ligandability

Cysteine 99 of Albumin

Cysteine 114 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 303 and 313 (279 and 289 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
4lb2
Structure name
x-ray study of human serum albumin complexed with idarubicin
Structure deposition date
2013-06-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
303
Residue number B
313
Peptide name
Albumin

Ligandability

Cysteine 303 of Albumin

Cysteine 313 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 501 and 511 (477 and 487 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
1bj5
Structure name
human serum albumin complexed with myristic acid
Structure deposition date
1998-07-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
501
Residue number B
511
Peptide name
Albumin

Ligandability

Cysteine 501 of Albumin

Cysteine 511 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 385 and 393 (361 and 369 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
4l9k
Structure name
x-ray study of human serum albumin complexed with camptothecin
Structure deposition date
2013-06-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
385
Residue number B
393
Peptide name
Albumin

Ligandability

Cysteine 385 of Albumin

Cysteine 393 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 289 and 313 (265 and 289 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
6a7p
Structure name
human serum albumin complexed with aripiprazole
Structure deposition date
2018-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
289
Residue number B
313
Peptide name
Albumin

Ligandability

Cysteine 289 of Albumin

Cysteine 313 of Albumin

A redox-regulated disulphide may form within Albumin between cysteines 224 and 269 (200 and 245 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
5vnw
Structure name
crystal structure of nb
Structure deposition date
2017-05-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P02768
Residue number A
224
Residue number B
269
Peptide name
Albumin

Ligandability

Cysteine 224 of Albumin

Cysteine 269 of Albumin

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