ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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T cell receptor gamma constant 2

Intramolecular
Cysteine 23 and cysteine 32
Cysteine 32 and cysteine 88
A redox-regulated disulphide may form within T cell receptor gamma constant 2 between cysteines 23 and 32 (23 and 97 respectively in this structure).

Details

Redox score ?
80
PDB code
1hxm
Structure name
crystal structure of a human vgamma9/vdelta2 t cell receptor
Structure deposition date
2001-01-16
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P03986
Residue number A
23
Residue number B
32
Peptide name
T cell receptor gamma constant 2

Ligandability

Cysteine 23 of T cell receptor gamma constant 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 32 of T cell receptor gamma constant 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 23 in protein A could not be asigned to a Uniprot residue.
A redox-regulated disulphide may form within T cell receptor gamma constant 2 between cysteines 32 and 88 (154 and 210 respectively in this structure).

Details

Redox score ?
78
PDB code
1hxm
Structure name
crystal structure of a human vgamma9/vdelta2 t cell receptor
Structure deposition date
2001-01-16
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P03986
Residue number A
32
Residue number B
88
Peptide name
T cell receptor gamma constant 2

Ligandability

Cysteine 32 of T cell receptor gamma constant 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 88 of T cell receptor gamma constant 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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