C4b-binding protein alpha chain
Intermolecular
Cysteine 546 and cysteine 558
Intramolecular
Cysteine 140 and cysteine 170
Cysteine 81 and cysteine 108
Cysteine 50 and cysteine 96
Cysteine 113 and cysteine 154
4b0f A 546 F 558
A redox-regulated disulphide may form between two units of C4b-binding protein alpha chain at cysteines 546 and 558.
Details
Redox score ?
87
PDB code
4b0f
Structure name
heptameric core complex structure of c4b-binding (c4bp) protein from human
Structure deposition date
2012-07-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide A name
C4b-binding protein alpha chain
Peptide B name
C4b-binding protein alpha chain
Peptide A accession
P04003
Peptide B accession
P04003
Peptide A residue number
546
Peptide B residue number
558
Ligandability
Cysteine 546 of C4b-binding protein alpha chain
Cysteine 558 of C4b-binding protein alpha chain
5hyt D 92 D 122
A redox-regulated disulphide may form within C4b-binding protein alpha chain between cysteines 140 and 170 (92 and 122 respectively in this structure).
Details
Redox score ?
88
PDB code
5hyt
Structure name
structure of human c4b-binidng protein alpha chain ccp domains 1 and 2 in complex with the hypervariable region of group a streptococcus m22 protein
Structure deposition date
2016-02-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04003
Residue number A
140
Residue number B
170
Peptide name
C4b-binding protein alpha chain
Ligandability
Cysteine 140 of C4b-binding protein alpha chain
Cysteine 170 of C4b-binding protein alpha chain
5hyp A 33 A 60
A redox-regulated disulphide may form within C4b-binding protein alpha chain between cysteines 81 and 108 (33 and 60 respectively in this structure).
Details
Redox score ?
86
PDB code
5hyp
Structure name
structure of human c4b-binding protein alpha cain ccp domains 1 and 2 in complex with the hypervariable region of group a streptococcus m28 protein
Structure deposition date
2016-02-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04003
Residue number A
81
Residue number B
108
Peptide name
C4b-binding protein alpha chain
Ligandability
Cysteine 81 of C4b-binding protein alpha chain
Cysteine 108 of C4b-binding protein alpha chain
5hyt B 2 B 48
A redox-regulated disulphide may form within C4b-binding protein alpha chain between cysteines 50 and 96 (2 and 48 respectively in this structure).
Details
Redox score ?
83
PDB code
5hyt
Structure name
structure of human c4b-binidng protein alpha chain ccp domains 1 and 2 in complex with the hypervariable region of group a streptococcus m22 protein
Structure deposition date
2016-02-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04003
Residue number A
50
Residue number B
96
Peptide name
C4b-binding protein alpha chain
Ligandability
Cysteine 50 of C4b-binding protein alpha chain
Cysteine 96 of C4b-binding protein alpha chain
5hyt B 65 B 106
A redox-regulated disulphide may form within C4b-binding protein alpha chain between cysteines 113 and 154 (65 and 106 respectively in this structure).
Details
Redox score ?
83
PDB code
5hyt
Structure name
structure of human c4b-binidng protein alpha chain ccp domains 1 and 2 in complex with the hypervariable region of group a streptococcus m22 protein
Structure deposition date
2016-02-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04003
Residue number A
113
Residue number B
154
Peptide name
C4b-binding protein alpha chain
Ligandability
Cysteine 113 of C4b-binding protein alpha chain
Cysteine 154 of C4b-binding protein alpha chain
If this tool was useful for finding a disulphide, please cite: