Platelet-derived growth factor subunit A
Intermolecular
Cysteine 132 and cysteine 123
Cysteine 133 and cysteine 123
Cysteine 123 and cysteine 140
Cysteine 179 and cysteine 123
Intramolecular
Cysteine 129 and cysteine 177
Cysteine 96 and cysteine 140
Cysteine 133 and cysteine 179
Cysteine 96 and cysteine 179
Cysteine 140 and cysteine 177
Cysteine 96 and cysteine 177
More...Cysteine 129 and cysteine 140
Cysteine 96 and cysteine 133
Cysteine 140 and cysteine 179
Cysteine 96 and cysteine 129
Cysteine 133 and cysteine 140
Cysteine 132 and cysteine 133
Cysteine 132 and cysteine 140
Cysteine 177 and cysteine 179
Cysteine 132 and cysteine 179
Cysteine 96 and cysteine 132
Cysteine 133 and cysteine 177
Cysteine 129 and cysteine 179
Cysteine 129 and cysteine 133
3mjk A 132 B 123
A redox-regulated disulphide may form between two units of Platelet-derived growth factor subunit A at cysteines 132 and 123.
Details
Redox score ?
81
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide A name
Platelet-derived growth factor subunit A
Peptide B name
Platelet-derived growth factor subunit A
Peptide A accession
P04085
Peptide B accession
P04085
Peptide A residue number
132
Peptide B residue number
123
Ligandability
Cysteine 132 of Platelet-derived growth factor subunit A
Cysteine 123 of Platelet-derived growth factor subunit A
3mjk A 133 B 123
A redox-regulated disulphide may form between two units of Platelet-derived growth factor subunit A at cysteines 133 and 123. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide A name
Platelet-derived growth factor subunit A
Peptide B name
Platelet-derived growth factor subunit A
Peptide A accession
P04085
Peptide B accession
P04085
Peptide A residue number
133
Peptide B residue number
123
Ligandability
Cysteine 133 of Platelet-derived growth factor subunit A
Cysteine 123 of Platelet-derived growth factor subunit A
3mjk E 123 F 140
A redox-regulated disulphide may form between two units of Platelet-derived growth factor subunit A at cysteines 123 and 140. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide A name
Platelet-derived growth factor subunit A
Peptide B name
Platelet-derived growth factor subunit A
Peptide A accession
P04085
Peptide B accession
P04085
Peptide A residue number
123
Peptide B residue number
140
Ligandability
Cysteine 123 of Platelet-derived growth factor subunit A
Cysteine 140 of Platelet-derived growth factor subunit A
3mjk A 179 B 123
A redox-regulated disulphide may form between two units of Platelet-derived growth factor subunit A at cysteines 179 and 123. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide A name
Platelet-derived growth factor subunit A
Peptide B name
Platelet-derived growth factor subunit A
Peptide A accession
P04085
Peptide B accession
P04085
Peptide A residue number
179
Peptide B residue number
123
Ligandability
Cysteine 179 of Platelet-derived growth factor subunit A
Cysteine 123 of Platelet-derived growth factor subunit A
3mjk Y 129 Y 177
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 129 and 177.
Details
Redox score ?
87
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
129
Residue number B
177
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 129 of Platelet-derived growth factor subunit A
Cysteine 177 of Platelet-derived growth factor subunit A
3mjk B 96 B 140
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 96 and 140.
Details
Redox score ?
86
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
96
Residue number B
140
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 96 of Platelet-derived growth factor subunit A
Cysteine 140 of Platelet-derived growth factor subunit A
3mjk X 133 X 179
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 133 and 179.
Details
Redox score ?
85
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
133
Residue number B
179
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 133 of Platelet-derived growth factor subunit A
Cysteine 179 of Platelet-derived growth factor subunit A
3mjk Y 96 Y 179
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 96 and 179.
Details
Redox score ?
74
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
96
Residue number B
179
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 96 of Platelet-derived growth factor subunit A
Cysteine 179 of Platelet-derived growth factor subunit A
3mjk E 140 E 177
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 140 and 177.
Details
Redox score ?
74
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
140
Residue number B
177
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 140 of Platelet-derived growth factor subunit A
Cysteine 177 of Platelet-derived growth factor subunit A
3mjk A 96 A 177
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 96 and 177.
Details
Redox score ?
69
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
96
Residue number B
177
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 96 of Platelet-derived growth factor subunit A
Cysteine 177 of Platelet-derived growth factor subunit A
3mjk X 129 X 140
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 129 and 140.
Details
Redox score ?
68
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
129
Residue number B
140
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 129 of Platelet-derived growth factor subunit A
Cysteine 140 of Platelet-derived growth factor subunit A
3mjk X 96 X 133
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 96 and 133.
Details
Redox score ?
67
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
96
Residue number B
133
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 96 of Platelet-derived growth factor subunit A
Cysteine 133 of Platelet-derived growth factor subunit A
3mjk Y 140 Y 179
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 140 and 179.
Details
Redox score ?
67
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
140
Residue number B
179
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 140 of Platelet-derived growth factor subunit A
Cysteine 179 of Platelet-derived growth factor subunit A
3mjk X 96 X 129
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 96 and 129.
Details
Redox score ?
63
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
6
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
96
Residue number B
129
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 96 of Platelet-derived growth factor subunit A
Cysteine 129 of Platelet-derived growth factor subunit A
3mjk A 133 A 140
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 133 and 140.
Details
Redox score ?
63
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
6
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
133
Residue number B
140
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 133 of Platelet-derived growth factor subunit A
Cysteine 140 of Platelet-derived growth factor subunit A
3mjk F 132 F 133
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 132 and 133. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
7
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
132
Residue number B
133
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 132 of Platelet-derived growth factor subunit A
Cysteine 133 of Platelet-derived growth factor subunit A
3mjk A 132 A 140
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 132 and 140. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
8
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
132
Residue number B
140
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 132 of Platelet-derived growth factor subunit A
Cysteine 140 of Platelet-derived growth factor subunit A
3mjk Y 177 Y 179
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 177 and 179. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
177
Residue number B
179
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 177 of Platelet-derived growth factor subunit A
Cysteine 179 of Platelet-derived growth factor subunit A
3mjk B 132 B 179
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 132 and 179. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
8
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
132
Residue number B
179
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 132 of Platelet-derived growth factor subunit A
Cysteine 179 of Platelet-derived growth factor subunit A
3mjk X 96 X 132
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 96 and 132. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
96
Residue number B
132
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 96 of Platelet-derived growth factor subunit A
Cysteine 132 of Platelet-derived growth factor subunit A
3mjk F 133 F 177
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 133 and 177. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
133
Residue number B
177
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 133 of Platelet-derived growth factor subunit A
Cysteine 177 of Platelet-derived growth factor subunit A
3mjk Y 129 Y 179
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 129 and 179. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
129
Residue number B
179
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 129 of Platelet-derived growth factor subunit A
Cysteine 179 of Platelet-derived growth factor subunit A
3mjk X 129 X 133
A redox-regulated disulphide may form within Platelet-derived growth factor subunit A between cysteines 129 and 133. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
3mjk
Structure name
structure of a growth factor precursor
Structure deposition date
2010-04-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04085
Residue number A
129
Residue number B
133
Peptide name
Platelet-derived growth factor subunit A
Ligandability
Cysteine 129 of Platelet-derived growth factor subunit A
Cysteine 133 of Platelet-derived growth factor subunit A
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