ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

Intramolecular
Cysteine 72 and cysteine 100 L
A redox-regulated disulphide may form within Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 between cysteines 72 and 100.

Details

Redox score ?
86
PDB code
8b6l
Structure name
subtomogram average of the human sec61-trap-osta-translocon
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P04844
Residue number A
72
Residue number B
100
Peptide name
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

Ligandability

Cysteine 72 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 100 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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