ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Interleukin-5

Intermolecular
Cysteine 105 and cysteine 63
A redox-regulated disulphide may form between two units of Interleukin-5 at cysteines 105 and 63.

Details

Redox score ?
84
PDB code
3va2
Structure name
crystal structure of human interleukin-5 in complex with its alpha receptor
Structure deposition date
2011-12-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide A name
Interleukin-5
Peptide B name
Interleukin-5
Peptide A accession
P05113
Peptide B accession
P05113
Peptide A residue number
105
Peptide B residue number
63

Ligandability

Cysteine 105 of Interleukin-5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 63 of Interleukin-5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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