Cytochrome P450 1A2

Intramolecular

A redox-regulated disulphide may form within Cytochrome P450 1A2 between cysteines 405 and 406. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2hi4

Structure name

crystal structure of human microsomal p450 1a2 in complex with alpha- naphthoflavone

Structure deposition date

2006-06-29

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P05177

Residue number A

405

Residue number B

406

Peptide name

Cytochrome P450 1A2

Ligandability

Cysteine 405 of Cytochrome P450 1A2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.