Complement C2
Intramolecular
Cysteine 24 and cysteine 64
Cysteine 51 and cysteine 84
Cysteine 151 and cysteine 191
Cysteine 117 and cysteine 144
Cysteine 177 and cysteine 204
Cysteine 89 and cysteine 131
Cysteine 584 and cysteine 600
Cysteine 675 and cysteine 705
Cysteine 492 and cysteine 508
Cysteine 638 and cysteine 665
Cysteine 463 and cysteine 581
3erb A 4 A 44
A redox-regulated disulphide may form within Complement C2 between cysteines 24 and 64 (4 and 44 respectively in this structure).
Details
Redox score ?
88
PDB code
3erb
Structure name
the crystal structure of c2b, a fragment of complement component c2 produced during c3-convertase formation
Structure deposition date
2008-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
24
Residue number B
64
Peptide name
Complement C2
Ligandability
Cysteine 24 of Complement C2
Cysteine 64 of Complement C2
3erb A 31 A 64
A redox-regulated disulphide may form within Complement C2 between cysteines 51 and 84 (31 and 64 respectively in this structure).
Details
Redox score ?
86
PDB code
3erb
Structure name
the crystal structure of c2b, a fragment of complement component c2 produced during c3-convertase formation
Structure deposition date
2008-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
51
Residue number B
84
Peptide name
Complement C2
Ligandability
Cysteine 51 of Complement C2
Cysteine 84 of Complement C2
3erb A 131 A 171
A redox-regulated disulphide may form within Complement C2 between cysteines 151 and 191 (131 and 171 respectively in this structure).
Details
Redox score ?
86
PDB code
3erb
Structure name
the crystal structure of c2b, a fragment of complement component c2 produced during c3-convertase formation
Structure deposition date
2008-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
151
Residue number B
191
Peptide name
Complement C2
Ligandability
Cysteine 151 of Complement C2
Cysteine 191 of Complement C2
3erb A 97 A 124
A redox-regulated disulphide may form within Complement C2 between cysteines 117 and 144 (97 and 124 respectively in this structure).
Details
Redox score ?
85
PDB code
3erb
Structure name
the crystal structure of c2b, a fragment of complement component c2 produced during c3-convertase formation
Structure deposition date
2008-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
117
Residue number B
144
Peptide name
Complement C2
Ligandability
Cysteine 117 of Complement C2
Cysteine 144 of Complement C2
3erb A 157 A 184
A redox-regulated disulphide may form within Complement C2 between cysteines 177 and 204 (157 and 184 respectively in this structure).
Details
Redox score ?
85
PDB code
3erb
Structure name
the crystal structure of c2b, a fragment of complement component c2 produced during c3-convertase formation
Structure deposition date
2008-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
177
Residue number B
204
Peptide name
Complement C2
Ligandability
Cysteine 177 of Complement C2
Cysteine 204 of Complement C2
3erb A 69 A 111
A redox-regulated disulphide may form within Complement C2 between cysteines 89 and 131 (69 and 111 respectively in this structure).
Details
Redox score ?
83
PDB code
3erb
Structure name
the crystal structure of c2b, a fragment of complement component c2 produced during c3-convertase formation
Structure deposition date
2008-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
89
Residue number B
131
Peptide name
Complement C2
Ligandability
Cysteine 89 of Complement C2
Cysteine 131 of Complement C2
2odq A 564 A 580
A redox-regulated disulphide may form within Complement C2 between cysteines 584 and 600 (564 and 580 respectively in this structure).
Details
Redox score ?
82
PDB code
2odq
Structure name
complement component c2a, the catalytic fragment of c3- and c5- convertase of human complement
Structure deposition date
2006-12-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
584
Residue number B
600
Peptide name
Complement C2
Ligandability
Cysteine 584 of Complement C2
Cysteine 600 of Complement C2
2i6s A 655 A 685
A redox-regulated disulphide may form within Complement C2 between cysteines 675 and 705 (655 and 685 respectively in this structure).
Details
Redox score ?
82
PDB code
2i6s
Structure name
complement component c2a
Structure deposition date
2006-08-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
675
Residue number B
705
Peptide name
Complement C2
Ligandability
Cysteine 675 of Complement C2
Cysteine 705 of Complement C2
2i6s A 472 A 488
A redox-regulated disulphide may form within Complement C2 between cysteines 492 and 508 (472 and 488 respectively in this structure).
Details
Redox score ?
82
PDB code
2i6s
Structure name
complement component c2a
Structure deposition date
2006-08-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
492
Residue number B
508
Peptide name
Complement C2
Ligandability
Cysteine 492 of Complement C2
Cysteine 508 of Complement C2
2i6s A 618 A 645
A redox-regulated disulphide may form within Complement C2 between cysteines 638 and 665 (618 and 645 respectively in this structure).
Details
Redox score ?
79
PDB code
2i6s
Structure name
complement component c2a
Structure deposition date
2006-08-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
638
Residue number B
665
Peptide name
Complement C2
Ligandability
Cysteine 638 of Complement C2
Cysteine 665 of Complement C2
2i6s A 443 A 561
A redox-regulated disulphide may form within Complement C2 between cysteines 463 and 581 (443 and 561 respectively in this structure).
Details
Redox score ?
78
PDB code
2i6s
Structure name
complement component c2a
Structure deposition date
2006-08-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
P06681
Residue number A
463
Residue number B
581
Peptide name
Complement C2
Ligandability
Cysteine 463 of Complement C2
Cysteine 581 of Complement C2
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