Uromodulin
Intermolecular
Cysteine 335 and cysteine 335
Intramolecular
Cysteine 32 and cysteine 41
Cysteine 120 and cysteine 135
Cysteine 52 and cysteine 63
Cysteine 300 and cysteine 315
Cysteine 571 and cysteine 578
Cysteine 155 and cysteine 170
Cysteine 94 and cysteine 106
Cysteine 35 and cysteine 50
Cysteine 137 and cysteine 148
More...Cysteine 112 and cysteine 126
Cysteine 366 and cysteine 389
Cysteine 77 and cysteine 92
Cysteine 297 and cysteine 306
Cysteine 69 and cysteine 83
Cysteine 527 and cysteine 582
Cysteine 174 and cysteine 267
Cysteine 150 and cysteine 161
Cysteine 195 and cysteine 282
Cysteine 217 and cysteine 255
Cysteine 317 and cysteine 347
Cysteine 248 and cysteine 256
Cysteine 223 and cysteine 287
Cysteine 35 and cysteine 41
Cysteine 506 and cysteine 566
Cysteine 300 and cysteine 306
Cysteine 150 and cysteine 155
Cysteine 150 and cysteine 170
Cysteine 120 and cysteine 126
Cysteine 77 and cysteine 83
Cysteine 32 and cysteine 35
Cysteine 297 and cysteine 300
Cysteine 155 and cysteine 161
Cysteine 161 and cysteine 170
Cysteine 306 and cysteine 315
Cysteine 41 and cysteine 50
Cysteine 126 and cysteine 135
Cysteine 112 and cysteine 120
Cysteine 255 and cysteine 256
Cysteine 83 and cysteine 92
4wrn A 435 B 435
A redox-regulated disulphide may form between two units of Uromodulin at cysteines 335 and 335 (435 and 435 respectively in this structure).
Details
Redox score ?
62
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide A name
Uromodulin
Peptide B name
Uromodulin
Peptide A accession
P07911
Peptide B accession
P07911
Peptide A residue number
335
Peptide B residue number
335
Ligandability
7q3n U 32 U 41
A redox-regulated disulphide may form within Uromodulin between cysteines 32 and 41.
Details
Redox score ?
88
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
32
Residue number B
41
Peptide name
Uromodulin
Ligandability
Cysteine 32 of Uromodulin
Cysteine 41 of Uromodulin
7q3n U 120 U 135
A redox-regulated disulphide may form within Uromodulin between cysteines 120 and 135.
Details
Redox score ?
88
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
120
Residue number B
135
Peptide name
Uromodulin
Ligandability
Cysteine 120 of Uromodulin
Cysteine 135 of Uromodulin
7pfp C 52 C 63
A redox-regulated disulphide may form within Uromodulin between cysteines 52 and 63.
Details
Redox score ?
88
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
52
Residue number B
63
Peptide name
Uromodulin
Ligandability
Cysteine 52 of Uromodulin
Cysteine 63 of Uromodulin
4wrn A 400 A 415
A redox-regulated disulphide may form within Uromodulin between cysteines 300 and 315 (400 and 415 respectively in this structure).
Details
Redox score ?
87
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
300
Residue number B
315
Peptide name
Uromodulin
Ligandability
Cysteine 300 of Uromodulin
Cysteine 315 of Uromodulin
4wrn A 671 A 678
A redox-regulated disulphide may form within Uromodulin between cysteines 571 and 578 (671 and 678 respectively in this structure).
Details
Redox score ?
87
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
571
Residue number B
578
Peptide name
Uromodulin
Ligandability
Cysteine 571 of Uromodulin
Cysteine 578 of Uromodulin
7pfp C 155 C 170
A redox-regulated disulphide may form within Uromodulin between cysteines 155 and 170.
Details
Redox score ?
87
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
155
Residue number B
170
Peptide name
Uromodulin
Ligandability
Cysteine 155 of Uromodulin
Cysteine 170 of Uromodulin
7q3n U 94 U 106
A redox-regulated disulphide may form within Uromodulin between cysteines 94 and 106.
Details
Redox score ?
87
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
94
Residue number B
106
Peptide name
Uromodulin
Ligandability
Cysteine 94 of Uromodulin
Cysteine 106 of Uromodulin
7pfp C 35 C 50
A redox-regulated disulphide may form within Uromodulin between cysteines 35 and 50.
Details
Redox score ?
87
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
35
Residue number B
50
Peptide name
Uromodulin
Ligandability
Cysteine 35 of Uromodulin
Cysteine 50 of Uromodulin
7pfp A 137 A 148
A redox-regulated disulphide may form within Uromodulin between cysteines 137 and 148.
Details
Redox score ?
86
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
137
Residue number B
148
Peptide name
Uromodulin
Ligandability
Cysteine 137 of Uromodulin
Cysteine 148 of Uromodulin
7q3n U 112 U 126
A redox-regulated disulphide may form within Uromodulin between cysteines 112 and 126.
Details
Redox score ?
86
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
112
Residue number B
126
Peptide name
Uromodulin
Ligandability
Cysteine 112 of Uromodulin
Cysteine 126 of Uromodulin
4wrn A 466 A 489
A redox-regulated disulphide may form within Uromodulin between cysteines 366 and 389 (466 and 489 respectively in this structure).
Details
Redox score ?
86
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
366
Residue number B
389
Peptide name
Uromodulin
Ligandability
Cysteine 366 of Uromodulin
Cysteine 389 of Uromodulin
7q3n U 77 U 92
A redox-regulated disulphide may form within Uromodulin between cysteines 77 and 92.
Details
Redox score ?
86
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
77
Residue number B
92
Peptide name
Uromodulin
Ligandability
Cysteine 77 of Uromodulin
Cysteine 92 of Uromodulin
4wrn A 397 A 406
A redox-regulated disulphide may form within Uromodulin between cysteines 297 and 306 (397 and 406 respectively in this structure).
Details
Redox score ?
86
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
297
Residue number B
306
Peptide name
Uromodulin
Ligandability
Cysteine 297 of Uromodulin
Cysteine 306 of Uromodulin
7q3n U 69 U 83
A redox-regulated disulphide may form within Uromodulin between cysteines 69 and 83.
Details
Redox score ?
85
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
69
Residue number B
83
Peptide name
Uromodulin
Ligandability
Cysteine 69 of Uromodulin
Cysteine 83 of Uromodulin
4wrn B 627 B 682
A redox-regulated disulphide may form within Uromodulin between cysteines 527 and 582 (627 and 682 respectively in this structure).
Details
Redox score ?
85
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
527
Residue number B
582
Peptide name
Uromodulin
Ligandability
Cysteine 527 of Uromodulin
Cysteine 582 of Uromodulin
7q3n U 174 U 267
A redox-regulated disulphide may form within Uromodulin between cysteines 174 and 267.
Details
Redox score ?
85
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
174
Residue number B
267
Peptide name
Uromodulin
Ligandability
Cysteine 174 of Uromodulin
Cysteine 267 of Uromodulin
7q3n U 150 U 161
A redox-regulated disulphide may form within Uromodulin between cysteines 150 and 161.
Details
Redox score ?
85
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
150
Residue number B
161
Peptide name
Uromodulin
Ligandability
Cysteine 150 of Uromodulin
Cysteine 161 of Uromodulin
7pfp A 195 A 282
A redox-regulated disulphide may form within Uromodulin between cysteines 195 and 282.
Details
Redox score ?
84
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
44
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
195
Residue number B
282
Peptide name
Uromodulin
Ligandability
Cysteine 195 of Uromodulin
Cysteine 282 of Uromodulin
7q3n U 217 U 255
A redox-regulated disulphide may form within Uromodulin between cysteines 217 and 255.
Details
Redox score ?
84
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
217
Residue number B
255
Peptide name
Uromodulin
Ligandability
Cysteine 217 of Uromodulin
Cysteine 255 of Uromodulin
4wrn A 417 A 447
A redox-regulated disulphide may form within Uromodulin between cysteines 317 and 347 (417 and 447 respectively in this structure).
Details
Redox score ?
84
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
317
Residue number B
347
Peptide name
Uromodulin
Ligandability
Cysteine 317 of Uromodulin
Cysteine 347 of Uromodulin
7pfp A 248 A 256
A redox-regulated disulphide may form within Uromodulin between cysteines 248 and 256.
Details
Redox score ?
84
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
248
Residue number B
256
Peptide name
Uromodulin
Ligandability
Cysteine 248 of Uromodulin
Cysteine 256 of Uromodulin
7pfp A 223 A 287
A redox-regulated disulphide may form within Uromodulin between cysteines 223 and 287.
Details
Redox score ?
80
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
223
Residue number B
287
Peptide name
Uromodulin
Ligandability
Cysteine 223 of Uromodulin
Cysteine 287 of Uromodulin
7q3n U 35 U 41
A redox-regulated disulphide may form within Uromodulin between cysteines 35 and 41.
Details
Redox score ?
77
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
35
Residue number B
41
Peptide name
Uromodulin
Ligandability
Cysteine 35 of Uromodulin
Cysteine 41 of Uromodulin
4wrn A 606 A 666
A redox-regulated disulphide may form within Uromodulin between cysteines 506 and 566 (606 and 666 respectively in this structure).
Details
Redox score ?
77
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
96
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
506
Residue number B
566
Peptide name
Uromodulin
Ligandability
Cysteine 506 of Uromodulin
Cysteine 566 of Uromodulin
4wrn A 400 A 406
A redox-regulated disulphide may form within Uromodulin between cysteines 300 and 306 (400 and 406 respectively in this structure).
Details
Redox score ?
74
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
300
Residue number B
306
Peptide name
Uromodulin
Ligandability
Cysteine 300 of Uromodulin
Cysteine 306 of Uromodulin
7pfp C 150 C 155
A redox-regulated disulphide may form within Uromodulin between cysteines 150 and 155.
Details
Redox score ?
74
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
150
Residue number B
155
Peptide name
Uromodulin
Ligandability
Cysteine 150 of Uromodulin
Cysteine 155 of Uromodulin
7q3n U 150 U 170
A redox-regulated disulphide may form within Uromodulin between cysteines 150 and 170.
Details
Redox score ?
74
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
150
Residue number B
170
Peptide name
Uromodulin
Ligandability
Cysteine 150 of Uromodulin
Cysteine 170 of Uromodulin
7pfp A 120 A 126
A redox-regulated disulphide may form within Uromodulin between cysteines 120 and 126.
Details
Redox score ?
74
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
120
Residue number B
126
Peptide name
Uromodulin
Ligandability
Cysteine 120 of Uromodulin
Cysteine 126 of Uromodulin
7pfp C 77 C 83
A redox-regulated disulphide may form within Uromodulin between cysteines 77 and 83.
Details
Redox score ?
73
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
77
Residue number B
83
Peptide name
Uromodulin
Ligandability
Cysteine 77 of Uromodulin
Cysteine 83 of Uromodulin
7q3n U 32 U 35
A redox-regulated disulphide may form within Uromodulin between cysteines 32 and 35.
Details
Redox score ?
71
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
32
Residue number B
35
Peptide name
Uromodulin
Ligandability
Cysteine 32 of Uromodulin
Cysteine 35 of Uromodulin
4wrn A 397 A 400
A redox-regulated disulphide may form within Uromodulin between cysteines 297 and 300 (397 and 400 respectively in this structure).
Details
Redox score ?
69
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
297
Residue number B
300
Peptide name
Uromodulin
Ligandability
Cysteine 297 of Uromodulin
Cysteine 300 of Uromodulin
7pfp A 155 A 161
A redox-regulated disulphide may form within Uromodulin between cysteines 155 and 161.
Details
Redox score ?
68
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
5
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
155
Residue number B
161
Peptide name
Uromodulin
Ligandability
Cysteine 155 of Uromodulin
Cysteine 161 of Uromodulin
7q3n U 161 U 170
A redox-regulated disulphide may form within Uromodulin between cysteines 161 and 170.
Details
Redox score ?
67
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
161
Residue number B
170
Peptide name
Uromodulin
Ligandability
Cysteine 161 of Uromodulin
Cysteine 170 of Uromodulin
4wrn A 406 A 415
A redox-regulated disulphide may form within Uromodulin between cysteines 306 and 315 (406 and 415 respectively in this structure).
Details
Redox score ?
66
PDB code
4wrn
Structure name
crystal structure of the polymerization region of human uromodulin/tamm-horsfall protein
Structure deposition date
2014-10-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
306
Residue number B
315
Peptide name
Uromodulin
Ligandability
Cysteine 306 of Uromodulin
Cysteine 315 of Uromodulin
7pfp C 41 C 50
A redox-regulated disulphide may form within Uromodulin between cysteines 41 and 50.
Details
Redox score ?
65
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
41
Residue number B
50
Peptide name
Uromodulin
Ligandability
Cysteine 41 of Uromodulin
Cysteine 50 of Uromodulin
7pfp C 126 C 135
A redox-regulated disulphide may form within Uromodulin between cysteines 126 and 135.
Details
Redox score ?
64
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
126
Residue number B
135
Peptide name
Uromodulin
Ligandability
Cysteine 126 of Uromodulin
Cysteine 135 of Uromodulin
7pfp A 112 A 120
A redox-regulated disulphide may form within Uromodulin between cysteines 112 and 120.
Details
Redox score ?
63
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
112
Residue number B
120
Peptide name
Uromodulin
Ligandability
Cysteine 112 of Uromodulin
Cysteine 120 of Uromodulin
7q3n U 255 U 256
A redox-regulated disulphide may form within Uromodulin between cysteines 255 and 256.
Details
Redox score ?
61
PDB code
7q3n
Structure name
cryo-em of the complex between human uromodulin (umod)/tamm-horsfall protein (thp) and the fimh lectin domain from uropathogenic e
Structure deposition date
2021-10-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
255
Residue number B
256
Peptide name
Uromodulin
Ligandability
Cysteine 255 of Uromodulin
Cysteine 256 of Uromodulin
7pfp C 83 C 92
A redox-regulated disulphide may form within Uromodulin between cysteines 83 and 92.
Details
Redox score ?
61
PDB code
7pfp
Structure name
full-length cryo-em structure of the native human uromodulin (umod) /tamm-horsfall protein (thp) filament
Structure deposition date
2021-08-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07911
Residue number A
83
Residue number B
92
Peptide name
Uromodulin
Ligandability
Cysteine 83 of Uromodulin
Cysteine 92 of Uromodulin
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