ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Annexin A6

Intramolecular
Cysteine 96 and cysteine 114
A redox-regulated disulphide may form within Annexin A6 between cysteines 96 and 114. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
27
PDB code
1m9i
Structure name
crystal structure of phosphorylation-mimicking mutant t356d of annexin vi
Structure deposition date
2002-07-29
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
12
% buried
97
Peptide accession
P08133
Residue number A
96
Residue number B
114
Peptide name
Annexin A6

Ligandability

Cysteine 96 of Annexin A6

Cysteine 114 of Annexin A6

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