Tumor necrosis factor receptor superfamily member 16
Intermolecular
Cysteine 257 and cysteine 257
Cysteine 379 and cysteine 379
Cysteine 381 and cysteine 241 of Tumor necrosis factor receptor type 1-associated DEATH domain protein
Intramolecular
Cysteine 171 and cysteine 189
Cysteine 168 and cysteine 181
Cysteine 126 and cysteine 139
Cysteine 129 and cysteine 147
Cysteine 45 and cysteine 58
Cysteine 90 and cysteine 108
Cysteine 48 and cysteine 65
More...Cysteine 68 and cysteine 84
Cysteine 33 and cysteine 44
Cysteine 110 and cysteine 123
Cysteine 87 and cysteine 100
Cysteine 150 and cysteine 165
Cysteine 44 and cysteine 45
Cysteine 33 and cysteine 45
Cysteine 68 and cysteine 87
Cysteine 33 and cysteine 58
Cysteine 48 and cysteine 84
Cysteine 129 and cysteine 150
Cysteine 44 and cysteine 58
Cysteine 150 and cysteine 181
Cysteine 150 and cysteine 168
Cysteine 147 and cysteine 150
Cysteine 110 and cysteine 126
Cysteine 65 and cysteine 84
Cysteine 48 and cysteine 68
Cysteine 110 and cysteine 139
Cysteine 129 and cysteine 165
Cysteine 139 and cysteine 147
Cysteine 108 and cysteine 110
Cysteine 68 and cysteine 100
Cysteine 48 and cysteine 58
Cysteine 181 and cysteine 189
Cysteine 87 and cysteine 90
Cysteine 84 and cysteine 87
Cysteine 147 and cysteine 165
Cysteine 65 and cysteine 68
Cysteine 58 and cysteine 65
2mic A 14 B 114
A redox-regulated disulphide may form between two units of Tumor necrosis factor receptor superfamily member 16 at cysteines 257 and 257 (14 and 114 respectively in this structure).
Details
Redox score ?
87
PDB code
2mic
Structure name
nmr structure of p75 transmembrane domain in dpc micelles
Structure deposition date
2013-12-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide A name
Tumor necrosis factor receptor superfamily member 16
Peptide B name
Tumor necrosis factor receptor superfamily member 16
Peptide A accession
P07174
Peptide B accession
P07174
Peptide A residue number
257
Peptide B residue number
257
Ligandability
Cysteine 257 of Tumor necrosis factor receptor superfamily member 16
Cysteine 257 of Tumor necrosis factor receptor superfamily member 16
4f44 A 47 B 47
A redox-regulated disulphide may form between two units of Tumor necrosis factor receptor superfamily member 16 at cysteines 379 and 379 (47 and 47 respectively in this structure).
Details
Redox score ?
81
PDB code
4f44
Structure name
neurotrophin p75ntr intracellular domain
Structure deposition date
2012-05-10
Thiol separation (Å)
2
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide A name
Tumor necrosis factor receptor superfamily member 16
Peptide B name
Tumor necrosis factor receptor superfamily member 16
Peptide A accession
P07174
Peptide B accession
P07174
Peptide A residue number
379
Peptide B residue number
379
Ligandability
7csq A 381 B 241
A redox-regulated disulphide may form between cysteine 381 of Tumor necrosis factor receptor superfamily member 16 and cysteine 241 of Tumor necrosis factor receptor type 1-associated DEATH domain protein. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7csq
Structure name
solution structure of the complex between p75ntr-dd and tradd-dd
Structure deposition date
2020-08-16
Thiol separation (Å)
8
Half-sphere exposure sum ?
71
Minimum pKa ?
10
% buried
74
Peptide A name
Tumor necrosis factor receptor superfamily member 16
Peptide B name
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Peptide A accession
P08138
Peptide B accession
Q15628
Peptide A residue number
381
Peptide B residue number
241
Ligandability
Cysteine 381 of Tumor necrosis factor receptor superfamily member 16
Cysteine 241 of Tumor necrosis factor receptor type 1-associated DEATH domain protein
3ij2 Y 142 Y 160
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 171 and 189 (142 and 160 respectively in this structure).
Details
Redox score ?
91
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
36
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
171
Residue number B
189
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 171 of Tumor necrosis factor receptor superfamily member 16
Cysteine 189 of Tumor necrosis factor receptor superfamily member 16
3ij2 Y 139 Y 152
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 168 and 181 (139 and 152 respectively in this structure).
Details
Redox score ?
89
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
168
Residue number B
181
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 168 of Tumor necrosis factor receptor superfamily member 16
Cysteine 181 of Tumor necrosis factor receptor superfamily member 16
3buk C 97 C 110
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 126 and 139 (97 and 110 respectively in this structure).
Details
Redox score ?
88
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
126
Residue number B
139
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 126 of Tumor necrosis factor receptor superfamily member 16
Cysteine 139 of Tumor necrosis factor receptor superfamily member 16
3ij2 X 100 X 118
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 129 and 147 (100 and 118 respectively in this structure).
Details
Redox score ?
88
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
129
Residue number B
147
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 16
Cysteine 147 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 16 X 29
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 45 and 58 (16 and 29 respectively in this structure).
Details
Redox score ?
88
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
45
Residue number B
58
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 45 of Tumor necrosis factor receptor superfamily member 16
Cysteine 58 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 61 X 79
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 90 and 108 (61 and 79 respectively in this structure).
Details
Redox score ?
88
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
90
Residue number B
108
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 90 of Tumor necrosis factor receptor superfamily member 16
Cysteine 108 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 19 X 36
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 48 and 65 (19 and 36 respectively in this structure).
Details
Redox score ?
88
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
48
Residue number B
65
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 48 of Tumor necrosis factor receptor superfamily member 16
Cysteine 65 of Tumor necrosis factor receptor superfamily member 16
3buk D 39 D 55
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 68 and 84 (39 and 55 respectively in this structure).
Details
Redox score ?
88
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
68
Residue number B
84
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 68 of Tumor necrosis factor receptor superfamily member 16
Cysteine 84 of Tumor necrosis factor receptor superfamily member 16
3ij2 Y 4 Y 15
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 33 and 44 (4 and 15 respectively in this structure).
Details
Redox score ?
87
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
33
Residue number B
44
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 33 of Tumor necrosis factor receptor superfamily member 16
Cysteine 44 of Tumor necrosis factor receptor superfamily member 16
3buk C 81 C 94
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 110 and 123 (81 and 94 respectively in this structure).
Details
Redox score ?
87
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
110
Residue number B
123
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 110 of Tumor necrosis factor receptor superfamily member 16
Cysteine 123 of Tumor necrosis factor receptor superfamily member 16
3buk C 58 C 71
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 87 and 100 (58 and 71 respectively in this structure).
Details
Redox score ?
87
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
87
Residue number B
100
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 87 of Tumor necrosis factor receptor superfamily member 16
Cysteine 100 of Tumor necrosis factor receptor superfamily member 16
3buk C 121 C 136
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 150 and 165 (121 and 136 respectively in this structure).
Details
Redox score ?
86
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
150
Residue number B
165
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 150 of Tumor necrosis factor receptor superfamily member 16
Cysteine 165 of Tumor necrosis factor receptor superfamily member 16
3buk C 15 C 16
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 44 and 45 (15 and 16 respectively in this structure).
Details
Redox score ?
67
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
5
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
44
Residue number B
45
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 44 of Tumor necrosis factor receptor superfamily member 16
Cysteine 45 of Tumor necrosis factor receptor superfamily member 16
3ij2 X 4 X 16
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 33 and 45 (4 and 16 respectively in this structure).
Details
Redox score ?
65
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
6
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
33
Residue number B
45
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 33 of Tumor necrosis factor receptor superfamily member 16
Cysteine 45 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 39 X 58
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 68 and 87 (39 and 58 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
68
Residue number B
87
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 68 of Tumor necrosis factor receptor superfamily member 16
Cysteine 87 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 4 X 29
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 33 and 58 (4 and 29 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
33
Residue number B
58
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 33 of Tumor necrosis factor receptor superfamily member 16
Cysteine 58 of Tumor necrosis factor receptor superfamily member 16
3ij2 Y 19 Y 55
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 48 and 84 (19 and 55 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
48
Residue number B
84
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 48 of Tumor necrosis factor receptor superfamily member 16
Cysteine 84 of Tumor necrosis factor receptor superfamily member 16
3ij2 X 100 X 121
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 129 and 150 (100 and 121 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
129
Residue number B
150
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 16
Cysteine 150 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 15 X 29
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 44 and 58 (15 and 29 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
44
Residue number B
58
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 44 of Tumor necrosis factor receptor superfamily member 16
Cysteine 58 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 121 X 152
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 150 and 181 (121 and 152 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
150
Residue number B
181
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 150 of Tumor necrosis factor receptor superfamily member 16
Cysteine 181 of Tumor necrosis factor receptor superfamily member 16
3buk C 121 C 139
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 150 and 168 (121 and 139 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
150
Residue number B
168
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 150 of Tumor necrosis factor receptor superfamily member 16
Cysteine 168 of Tumor necrosis factor receptor superfamily member 16
3buk D 118 D 121
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 147 and 150 (118 and 121 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
147
Residue number B
150
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 147 of Tumor necrosis factor receptor superfamily member 16
Cysteine 150 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 81 X 97
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 110 and 126 (81 and 97 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
110
Residue number B
126
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 110 of Tumor necrosis factor receptor superfamily member 16
Cysteine 126 of Tumor necrosis factor receptor superfamily member 16
3buk D 36 D 55
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 65 and 84 (36 and 55 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
65
Residue number B
84
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 65 of Tumor necrosis factor receptor superfamily member 16
Cysteine 84 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 19 X 39
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 48 and 68 (19 and 39 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
48
Residue number B
68
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 48 of Tumor necrosis factor receptor superfamily member 16
Cysteine 68 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 81 X 110
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 110 and 139 (81 and 110 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
110
Residue number B
139
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 110 of Tumor necrosis factor receptor superfamily member 16
Cysteine 139 of Tumor necrosis factor receptor superfamily member 16
3ij2 X 100 X 136
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 129 and 165 (100 and 136 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
129
Residue number B
165
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 16
Cysteine 165 of Tumor necrosis factor receptor superfamily member 16
3ij2 X 110 X 118
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 139 and 147 (110 and 118 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
139
Residue number B
147
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 139 of Tumor necrosis factor receptor superfamily member 16
Cysteine 147 of Tumor necrosis factor receptor superfamily member 16
3buk C 79 C 81
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 108 and 110 (79 and 81 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
108
Residue number B
110
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 108 of Tumor necrosis factor receptor superfamily member 16
Cysteine 110 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 39 X 71
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 68 and 100 (39 and 71 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
68
Residue number B
100
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 68 of Tumor necrosis factor receptor superfamily member 16
Cysteine 100 of Tumor necrosis factor receptor superfamily member 16
3ij2 Y 19 Y 29
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 48 and 58 (19 and 29 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
48
Residue number B
58
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 48 of Tumor necrosis factor receptor superfamily member 16
Cysteine 58 of Tumor necrosis factor receptor superfamily member 16
3buk D 152 D 160
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 181 and 189 (152 and 160 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
181
Residue number B
189
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 181 of Tumor necrosis factor receptor superfamily member 16
Cysteine 189 of Tumor necrosis factor receptor superfamily member 16
3ij2 X 58 X 61
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 87 and 90 (58 and 61 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
3ij2
Structure name
ligand-receptor structure
Structure deposition date
2009-08-03
Thiol separation (Å)
10
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
87
Residue number B
90
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 87 of Tumor necrosis factor receptor superfamily member 16
Cysteine 90 of Tumor necrosis factor receptor superfamily member 16
3buk D 55 D 58
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 84 and 87 (55 and 58 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
84
Residue number B
87
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 84 of Tumor necrosis factor receptor superfamily member 16
Cysteine 87 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 118 X 136
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 147 and 165 (118 and 136 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
147
Residue number B
165
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 147 of Tumor necrosis factor receptor superfamily member 16
Cysteine 165 of Tumor necrosis factor receptor superfamily member 16
1sg1 X 36 X 39
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 65 and 68 (36 and 39 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
1sg1
Structure name
crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Structure deposition date
2004-02-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
65
Residue number B
68
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 65 of Tumor necrosis factor receptor superfamily member 16
Cysteine 68 of Tumor necrosis factor receptor superfamily member 16
3buk D 29 D 36
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 16 between cysteines 58 and 65 (29 and 36 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3buk
Structure name
crystal structure of the neurotrophin-3 and p75ntr symmetrical complex
Structure deposition date
2008-01-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P07174
Residue number A
58
Residue number B
65
Peptide name
Tumor necrosis factor receptor superfamily member 16
Ligandability
Cysteine 58 of Tumor necrosis factor receptor superfamily member 16
Cysteine 65 of Tumor necrosis factor receptor superfamily member 16
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