ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Low affinity immunoglobulin gamma Fc region receptor III-A

Intramolecular
Cysteine 47 and cysteine 89
Cysteine 128 and cysteine 172
A redox-regulated disulphide may form within Low affinity immunoglobulin gamma Fc region receptor III-A between cysteines 47 and 89 (29 and 71 respectively in this structure).

Details

Redox score ?
84
PDB code
5ml9
Structure name
cocrystal structure of fc gamma receptor iiia interacting with affimer f4, a specific binding protein which blocks igg binding to the receptor
Structure deposition date
2016-12-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08637
Residue number A
47
Residue number B
89
Peptide name
Low affinity immunoglobulin gamma Fc region receptor III-A

Ligandability

Cysteine 47 of Low affinity immunoglobulin gamma Fc region receptor III-A

Cysteine 89 of Low affinity immunoglobulin gamma Fc region receptor III-A

A redox-regulated disulphide may form within Low affinity immunoglobulin gamma Fc region receptor III-A between cysteines 128 and 172 (110 and 154 respectively in this structure).

Details

Redox score ?
80
PDB code
5mn2
Structure name
cocrystal structure of fc gamma receptor iiia interacting with affimer g3, a specific binding protein which blocks igg binding to the receptor
Structure deposition date
2016-12-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08637
Residue number A
128
Residue number B
172
Peptide name
Low affinity immunoglobulin gamma Fc region receptor III-A

Ligandability

Cysteine 128 of Low affinity immunoglobulin gamma Fc region receptor III-A

Cysteine 172 of Low affinity immunoglobulin gamma Fc region receptor III-A

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