Growth-regulated alpha protein
Intramolecular
Cysteine 43 and cysteine 69
Cysteine 43 and cysteine 45
Cysteine 45 and cysteine 85
Cysteine 45 and cysteine 69
Cysteine 69 and cysteine 85
Cysteine 43 and cysteine 85
1msg B 9 B 35
A redox-regulated disulphide may form within Growth-regulated alpha protein between cysteines 43 and 69 (9 and 35 respectively in this structure).
Details
Redox score ?
86
PDB code
1msg
Structure name
solution structure of gro(slash)melanoma growth stimulatory activity determined by 1h nmr spectroscopy
Structure deposition date
1995-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
8
% buried
5
Peptide accession
P09341
Residue number A
43
Residue number B
69
Peptide name
Growth-regulated alpha protein
Ligandability
Cysteine 43 of Growth-regulated alpha protein
Cysteine 69 of Growth-regulated alpha protein
1msg B 9 B 11
A redox-regulated disulphide may form within Growth-regulated alpha protein between cysteines 43 and 45 (9 and 11 respectively in this structure).
Details
Redox score ?
76
PDB code
1msg
Structure name
solution structure of gro(slash)melanoma growth stimulatory activity determined by 1h nmr spectroscopy
Structure deposition date
1995-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
11
% buried
15
Peptide accession
P09341
Residue number A
43
Residue number B
45
Peptide name
Growth-regulated alpha protein
Ligandability
Cysteine 43 of Growth-regulated alpha protein
Cysteine 45 of Growth-regulated alpha protein
1msh B 11 B 51
A redox-regulated disulphide may form within Growth-regulated alpha protein between cysteines 45 and 85 (11 and 51 respectively in this structure).
Details
Redox score ?
70
PDB code
1msh
Structure name
solution structure of gro(slash)melanoma growth stimulatory activity determined by 1h nmr spectroscopy
Structure deposition date
1995-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
11
% buried
35
Peptide accession
P09341
Residue number A
45
Residue number B
85
Peptide name
Growth-regulated alpha protein
Ligandability
Cysteine 45 of Growth-regulated alpha protein
Cysteine 85 of Growth-regulated alpha protein
1msg A 11 A 35
A redox-regulated disulphide may form within Growth-regulated alpha protein between cysteines 45 and 69 (11 and 35 respectively in this structure).
Details
Redox score ?
61
PDB code
1msg
Structure name
solution structure of gro(slash)melanoma growth stimulatory activity determined by 1h nmr spectroscopy
Structure deposition date
1995-01-25
Thiol separation (Å)
7
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09341
Residue number A
45
Residue number B
69
Peptide name
Growth-regulated alpha protein
Ligandability
Cysteine 45 of Growth-regulated alpha protein
Cysteine 69 of Growth-regulated alpha protein
1msh B 35 B 51
A redox-regulated disulphide may form within Growth-regulated alpha protein between cysteines 69 and 85 (35 and 51 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
1msh
Structure name
solution structure of gro(slash)melanoma growth stimulatory activity determined by 1h nmr spectroscopy
Structure deposition date
1995-01-25
Thiol separation (Å)
9
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
26
Peptide accession
P09341
Residue number A
69
Residue number B
85
Peptide name
Growth-regulated alpha protein
Ligandability
Cysteine 69 of Growth-regulated alpha protein
Cysteine 85 of Growth-regulated alpha protein
1msh A 9 A 51
A redox-regulated disulphide may form within Growth-regulated alpha protein between cysteines 43 and 85 (9 and 51 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
1msh
Structure name
solution structure of gro(slash)melanoma growth stimulatory activity determined by 1h nmr spectroscopy
Structure deposition date
1995-01-25
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09341
Residue number A
43
Residue number B
85
Peptide name
Growth-regulated alpha protein
Ligandability
Cysteine 43 of Growth-regulated alpha protein
Cysteine 85 of Growth-regulated alpha protein
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