Glutathione S-transferase Mu 1
Intermolecular
Cysteine 87 and cysteine 87
Cysteine 78 and cysteine 78
Intramolecular
Cysteine 78 and cysteine 87
1xwk A 86 C 86
A redox-regulated disulphide may form between two units of Glutathione S-transferase Mu 1 at cysteines 87 and 87 (86 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
1xwk
Structure name
2
Structure deposition date
2004-11-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
8
% buried
96
Peptide A name
Glutathione S-transferase Mu 1
Peptide B name
Glutathione S-transferase Mu 1
Peptide A accession
P09488
Peptide B accession
P09488
Peptide A residue number
87
Peptide B residue number
87
Ligandability
2f3m C 77 D 77
A redox-regulated disulphide may form between two units of Glutathione S-transferase Mu 1 at cysteines 78 and 78 (77 and 77 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
2f3m
Structure name
structure of human glutathione s-transferase m1a-1a complexed with 1- (s-(glutathionyl)-2,4,6-trinitrocyclohexadienate anion
Structure deposition date
2005-11-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide A name
Glutathione S-transferase Mu 1
Peptide B name
Glutathione S-transferase Mu 1
Peptide A accession
P09488
Peptide B accession
P09488
Peptide A residue number
78
Peptide B residue number
78
Ligandability
1gtu C 77 C 86
A redox-regulated disulphide may form within Glutathione S-transferase Mu 1 between cysteines 78 and 87 (77 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
1gtu
Structure name
ligand-free human glutathione s-transferase m1a-1a
Structure deposition date
1998-06-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
90
Peptide accession
P09488
Residue number A
78
Residue number B
87
Peptide name
Glutathione S-transferase Mu 1
Ligandability
Cysteine 78 of Glutathione S-transferase Mu 1
Cysteine 87 of Glutathione S-transferase Mu 1
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