T-cell surface glycoprotein CD3 gamma chain
Intermolecular
Cysteine 122 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 107
Cysteine 122 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 104
Cysteine 119 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 107
Cysteine 119 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 104
Intramolecular
Cysteine 104 and cysteine 107
Cysteine 46 and cysteine 87
7fjd f 122 g 107
A redox-regulated disulphide may form between cysteine 122 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 107 of T-cell surface glycoprotein CD3 gamma chain.
Details
Redox score ?
66
PDB code
7fjd
Structure name
cryo-em structure of a membrane protein(wt)
Structure deposition date
2021-08-03
Thiol separation (Å)
6
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide A name
T-cell surface glycoprotein CD3 epsilon chain
Peptide B name
T-cell surface glycoprotein CD3 gamma chain
Peptide A accession
P07766
Peptide B accession
P09693
Peptide A residue number
122
Peptide B residue number
107
Ligandability
Cysteine 122 of T-cell surface glycoprotein CD3 epsilon chain
Cysteine 107 of T-cell surface glycoprotein CD3 gamma chain
7fjf f 122 g 104
A redox-regulated disulphide may form between cysteine 122 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 104 of T-cell surface glycoprotein CD3 gamma chain.
Details
Redox score ?
64
PDB code
7fjf
Structure name
cryo-em structure of a membrane protein(cs)
Structure deposition date
2021-08-03
Thiol separation (Å)
6
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide A name
T-cell surface glycoprotein CD3 epsilon chain
Peptide B name
T-cell surface glycoprotein CD3 gamma chain
Peptide A accession
P07766
Peptide B accession
P09693
Peptide A residue number
122
Peptide B residue number
104
Ligandability
Cysteine 122 of T-cell surface glycoprotein CD3 epsilon chain
Cysteine 104 of T-cell surface glycoprotein CD3 gamma chain
6jxr f 119 g 107
A redox-regulated disulphide may form between cysteine 119 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 107 of T-cell surface glycoprotein CD3 gamma chain.
Details
Redox score ?
63
PDB code
6jxr
Structure name
structure of human t cell receptor-cd3 complex
Structure deposition date
2019-04-24
Thiol separation (Å)
6
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide A name
T-cell surface glycoprotein CD3 epsilon chain
Peptide B name
T-cell surface glycoprotein CD3 gamma chain
Peptide A accession
P07766
Peptide B accession
P09693
Peptide A residue number
119
Peptide B residue number
107
Ligandability
Cysteine 119 of T-cell surface glycoprotein CD3 epsilon chain
Cysteine 107 of T-cell surface glycoprotein CD3 gamma chain
6jxr f 119 g 104
A redox-regulated disulphide may form between cysteine 119 of T-cell surface glycoprotein CD3 epsilon chain and cysteine 104 of T-cell surface glycoprotein CD3 gamma chain.
Details
Redox score ?
63
PDB code
6jxr
Structure name
structure of human t cell receptor-cd3 complex
Structure deposition date
2019-04-24
Thiol separation (Å)
6
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide A name
T-cell surface glycoprotein CD3 epsilon chain
Peptide B name
T-cell surface glycoprotein CD3 gamma chain
Peptide A accession
P07766
Peptide B accession
P09693
Peptide A residue number
119
Peptide B residue number
104
Ligandability
Cysteine 119 of T-cell surface glycoprotein CD3 epsilon chain
Cysteine 104 of T-cell surface glycoprotein CD3 gamma chain
7phr C 82 C 85
A redox-regulated disulphide may form within T-cell surface glycoprotein CD3 gamma chain between cysteines 104 and 107 (82 and 85 respectively in this structure).
Details
Redox score ?
83
PDB code
7phr
Structure name
structure of a fully assembled t-cell receptor engaging a tumor- associated peptide-mhc i
Structure deposition date
2021-08-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09693
Residue number A
104
Residue number B
107
Peptide name
T-cell surface glycoprotein CD3 gamma chain
Ligandability
Cysteine 104 of T-cell surface glycoprotein CD3 gamma chain
Cysteine 107 of T-cell surface glycoprotein CD3 gamma chain
6jxr g 46 g 87
A redox-regulated disulphide may form within T-cell surface glycoprotein CD3 gamma chain between cysteines 46 and 87.
Details
Redox score ?
82
PDB code
6jxr
Structure name
structure of human t cell receptor-cd3 complex
Structure deposition date
2019-04-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09693
Residue number A
46
Residue number B
87
Peptide name
T-cell surface glycoprotein CD3 gamma chain
Ligandability
Cysteine 46 of T-cell surface glycoprotein CD3 gamma chain
Cysteine 87 of T-cell surface glycoprotein CD3 gamma chain
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