Tumor-associated calcium signal transducer 2
Intramolecular
Cysteine 36 and cysteine 66
Cysteine 34 and cysteine 53
Cysteine 119 and cysteine 125
Cysteine 44 and cysteine 55
Cysteine 127 and cysteine 145
Cysteine 73 and cysteine 108
Cysteine 53 and cysteine 55
Cysteine 44 and cysteine 53
Cysteine 36 and cysteine 55
Cysteine 44 and cysteine 66
More...Cysteine 36 and cysteine 44
Cysteine 34 and cysteine 44
Cysteine 55 and cysteine 66
Cysteine 34 and cysteine 55
Cysteine 53 and cysteine 66
Cysteine 125 and cysteine 145
Cysteine 119 and cysteine 145
Cysteine 36 and cysteine 53
Cysteine 34 and cysteine 66
Cysteine 125 and cysteine 127
Cysteine 34 and cysteine 36
Cysteine 119 and cysteine 127
7e5m B 36 B 66
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 36 and 66.
Details
Redox score ?
89
PDB code
7e5m
Structure name
crystal structure of trans assembled human trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
36
Residue number B
66
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 36 of Tumor-associated calcium signal transducer 2
Cysteine 66 of Tumor-associated calcium signal transducer 2
7e5n D 34 D 53
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 34 and 53.
Details
Redox score ?
88
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
39
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
34
Residue number B
53
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 34 of Tumor-associated calcium signal transducer 2
Cysteine 53 of Tumor-associated calcium signal transducer 2
7e5n A 119 A 125
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 119 and 125.
Details
Redox score ?
85
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
119
Residue number B
125
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 119 of Tumor-associated calcium signal transducer 2
Cysteine 125 of Tumor-associated calcium signal transducer 2
7e5n A 44 A 55
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 44 and 55.
Details
Redox score ?
85
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
44
Residue number B
55
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 44 of Tumor-associated calcium signal transducer 2
Cysteine 55 of Tumor-associated calcium signal transducer 2
7pee D 127 D 145
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 127 and 145.
Details
Redox score ?
84
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
127
Residue number B
145
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 127 of Tumor-associated calcium signal transducer 2
Cysteine 145 of Tumor-associated calcium signal transducer 2
7pee B 73 B 108
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 73 and 108.
Details
Redox score ?
83
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
73
Residue number B
108
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 73 of Tumor-associated calcium signal transducer 2
Cysteine 108 of Tumor-associated calcium signal transducer 2
7pee D 53 D 55
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 53 and 55.
Details
Redox score ?
76
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
53
Residue number B
55
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 53 of Tumor-associated calcium signal transducer 2
Cysteine 55 of Tumor-associated calcium signal transducer 2
7e5n D 44 D 53
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 44 and 53.
Details
Redox score ?
75
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
44
Residue number B
53
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 44 of Tumor-associated calcium signal transducer 2
Cysteine 53 of Tumor-associated calcium signal transducer 2
7e5m A 36 A 55
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 36 and 55.
Details
Redox score ?
73
PDB code
7e5m
Structure name
crystal structure of trans assembled human trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
36
Residue number B
55
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 36 of Tumor-associated calcium signal transducer 2
Cysteine 55 of Tumor-associated calcium signal transducer 2
7pee B 44 B 66
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 44 and 66.
Details
Redox score ?
71
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
5
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
44
Residue number B
66
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 44 of Tumor-associated calcium signal transducer 2
Cysteine 66 of Tumor-associated calcium signal transducer 2
7e5m B 36 B 44
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 36 and 44.
Details
Redox score ?
70
PDB code
7e5m
Structure name
crystal structure of trans assembled human trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
36
Residue number B
44
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 36 of Tumor-associated calcium signal transducer 2
Cysteine 44 of Tumor-associated calcium signal transducer 2
7e5n A 34 A 44
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 34 and 44.
Details
Redox score ?
68
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
34
Residue number B
44
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 34 of Tumor-associated calcium signal transducer 2
Cysteine 44 of Tumor-associated calcium signal transducer 2
7e5n A 55 A 66
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 55 and 66.
Details
Redox score ?
68
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
55
Residue number B
66
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 55 of Tumor-associated calcium signal transducer 2
Cysteine 66 of Tumor-associated calcium signal transducer 2
7pee A 34 A 55
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 34 and 55.
Details
Redox score ?
67
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
5
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
34
Residue number B
55
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 34 of Tumor-associated calcium signal transducer 2
Cysteine 55 of Tumor-associated calcium signal transducer 2
7pee B 53 B 66
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 53 and 66. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
53
Residue number B
66
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 53 of Tumor-associated calcium signal transducer 2
Cysteine 66 of Tumor-associated calcium signal transducer 2
7pee C 125 C 145
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 125 and 145. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
125
Residue number B
145
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 125 of Tumor-associated calcium signal transducer 2
Cysteine 145 of Tumor-associated calcium signal transducer 2
7e5n D 119 D 145
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 119 and 145. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
119
Residue number B
145
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 119 of Tumor-associated calcium signal transducer 2
Cysteine 145 of Tumor-associated calcium signal transducer 2
7e5m B 36 B 53
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 36 and 53. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7e5m
Structure name
crystal structure of trans assembled human trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
36
Residue number B
53
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 36 of Tumor-associated calcium signal transducer 2
Cysteine 53 of Tumor-associated calcium signal transducer 2
7pee B 34 B 66
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 34 and 66. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7pee
Structure name
crystal structure of extracellular part of human trop2
Structure deposition date
2021-08-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
34
Residue number B
66
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 34 of Tumor-associated calcium signal transducer 2
Cysteine 66 of Tumor-associated calcium signal transducer 2
7e5n B 125 B 127
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 125 and 127. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
125
Residue number B
127
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 125 of Tumor-associated calcium signal transducer 2
Cysteine 127 of Tumor-associated calcium signal transducer 2
7e5m B 34 B 36
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 34 and 36. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7e5m
Structure name
crystal structure of trans assembled human trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
34
Residue number B
36
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 34 of Tumor-associated calcium signal transducer 2
Cysteine 36 of Tumor-associated calcium signal transducer 2
7e5n B 119 B 127
A redox-regulated disulphide may form within Tumor-associated calcium signal transducer 2 between cysteines 119 and 127. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
7e5n
Structure name
crystal structure of cis assembled trop-2
Structure deposition date
2021-02-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P09758
Residue number A
119
Residue number B
127
Peptide name
Tumor-associated calcium signal transducer 2
Ligandability
Cysteine 119 of Tumor-associated calcium signal transducer 2
Cysteine 127 of Tumor-associated calcium signal transducer 2
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