Granulocyte colony-stimulating factor

Intramolecular

A redox-regulated disulphide may form within Granulocyte colony-stimulating factor between cysteines 57 and 63 (37 and 43 respectively in this structure).

Details

Redox score ?

PDB code

1bgc

Structure name

crystal structure of canine and bovine granulocyte-colony stimulating factor (g-csf)

Structure deposition date

1993-04-27

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

P35833

Residue number A

Residue number B

Peptide name

Granulocyte colony-stimulating factor

Ligandability

Cysteine 57 of Granulocyte colony-stimulating factor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 63 of Granulocyte colony-stimulating factor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Granulocyte colony-stimulating factor between cysteines 69 and 75 (37 and 43 respectively in this structure).

Details

Redox score ?

PDB code

1pgr

Structure name

2:2 complex of g-csf with its receptor

Structure deposition date

1999-03-08

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

P09919

Residue number A

Residue number B

Peptide name

Granulocyte colony-stimulating factor

Ligandability

Cysteine 69 of Granulocyte colony-stimulating factor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 75 of Granulocyte colony-stimulating factor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Granulocyte colony-stimulating factor between cysteines 97 and 107 (65 and 75 respectively in this structure).