ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Wee1-like protein kinase 2

Intramolecular
Cysteine 292 and cysteine 348
A redox-regulated disulphide may form within Wee1-like protein kinase 2 between cysteines 292 and 348.

Details

Redox score ?
83
PDB code
5vdk
Structure name
crystal structure of human wee2 kinase domain in complex with mk1775
Structure deposition date
2017-04-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
6
% buried
68
Peptide accession
P0C1S8
Residue number A
292
Residue number B
348
Peptide name
Wee1-like protein kinase 2

Ligandability

Cysteine 292 of Wee1-like protein kinase 2

Cysteine 348 of Wee1-like protein kinase 2

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