a tool for identifying drug-targetable redox-active disulphides

Chromogranin-A

Intramolecular

Cysteine 1 and cysteine 15

A redox-regulated disulphide may form within Chromogranin-A between cysteines 1 and 15.

Details

Redox score ?

nan

PDB code

Structure name

solution structure of ss-cyclized catestatin fragment from chromogranin a

Structure deposition date

2002-10-24

Thiol separation (Å)

2

Half-sphere exposure sum ?

nan

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

1

Residue number B

15

Peptide name

Chromogranin-A

Ligandability

Cysteine 1 of Chromogranin-A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 15 of Chromogranin-A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1 in protein A could not be asigned to a Uniprot residue.

Cysteine 15 in protein B could not be asigned to a Uniprot residue.

If this tool was useful for finding a disulphide, please cite: