Platelet factor 4 variant
Intermolecular
Cysteine 86 and cysteine 86
Cysteine 46 and cysteine 86
Cysteine 46 and cysteine 46
Intramolecular
Cysteine 44 and cysteine 70
Cysteine 46 and cysteine 70
Cysteine 44 and cysteine 46
Cysteine 70 and cysteine 86
Cysteine 44 and cysteine 86
4hsv B 52 C 52
A redox-regulated disulphide may form between two units of Platelet factor 4 variant at cysteines 86 and 86 (52 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide A name
Platelet factor 4 variant
Peptide B name
Platelet factor 4 variant
Peptide A accession
P10720
Peptide B accession
P10720
Peptide A residue number
86
Peptide B residue number
86
Ligandability
4hsv B 12 C 52
A redox-regulated disulphide may form between two units of Platelet factor 4 variant at cysteines 46 and 86 (12 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide A name
Platelet factor 4 variant
Peptide B name
Platelet factor 4 variant
Peptide A accession
P10720
Peptide B accession
P10720
Peptide A residue number
46
Peptide B residue number
86
Ligandability
Cysteine 46 of Platelet factor 4 variant
Cysteine 86 of Platelet factor 4 variant
4hsv B 12 C 12
A redox-regulated disulphide may form between two units of Platelet factor 4 variant at cysteines 46 and 46 (12 and 12 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
10
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide A name
Platelet factor 4 variant
Peptide B name
Platelet factor 4 variant
Peptide A accession
P10720
Peptide B accession
P10720
Peptide A residue number
46
Peptide B residue number
46
Ligandability
4hsv C 10 C 36
A redox-regulated disulphide may form within Platelet factor 4 variant between cysteines 44 and 70 (10 and 36 respectively in this structure).
Details
Redox score ?
87
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P10720
Residue number A
44
Residue number B
70
Peptide name
Platelet factor 4 variant
Ligandability
Cysteine 44 of Platelet factor 4 variant
Cysteine 70 of Platelet factor 4 variant
4hsv C 12 C 36
A redox-regulated disulphide may form within Platelet factor 4 variant between cysteines 46 and 70 (12 and 36 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P10720
Residue number A
46
Residue number B
70
Peptide name
Platelet factor 4 variant
Ligandability
Cysteine 46 of Platelet factor 4 variant
Cysteine 70 of Platelet factor 4 variant
4hsv D 10 D 12
A redox-regulated disulphide may form within Platelet factor 4 variant between cysteines 44 and 46 (10 and 12 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
8
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P10720
Residue number A
44
Residue number B
46
Peptide name
Platelet factor 4 variant
Ligandability
Cysteine 44 of Platelet factor 4 variant
Cysteine 46 of Platelet factor 4 variant
4hsv B 36 B 52
A redox-regulated disulphide may form within Platelet factor 4 variant between cysteines 70 and 86 (36 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P10720
Residue number A
70
Residue number B
86
Peptide name
Platelet factor 4 variant
Ligandability
Cysteine 70 of Platelet factor 4 variant
Cysteine 86 of Platelet factor 4 variant
4hsv D 10 D 52
A redox-regulated disulphide may form within Platelet factor 4 variant between cysteines 44 and 86 (10 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
4hsv
Structure name
crystal structure of cxcl4l1
Structure deposition date
2012-10-30
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P10720
Residue number A
44
Residue number B
86
Peptide name
Platelet factor 4 variant
Ligandability
Cysteine 44 of Platelet factor 4 variant
Cysteine 86 of Platelet factor 4 variant
If this tool was useful for finding a disulphide, please cite: