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Cation-independent mannose-6-phosphate receptor

Intramolecular
Cysteine 1470 and cysteine 1503
Cysteine 1759 and cysteine 1792
Cysteine 883 and cysteine 918
Cysteine 2082 and cysteine 2113
Cysteine 1186 and cysteine 1214
Cysteine 117 and cysteine 149
Cysteine 581 and cysteine 614
Cysteine 1328 and cysteine 1358 L
Cysteine 984 and cysteine 995
Cysteine 275 and cysteine 306
More...
Cysteine 1485 and cysteine 1515
Cysteine 2241 and cysteine 2275
Cysteine 1766 and cysteine 1795
Cysteine 2257 and cysteine 2287
Cysteine 134 and cysteine 161
Cysteine 2197 and cysteine 2203
Cysteine 540 and cysteine 547 L
Cysteine 1917 and cysteine 1942
Cysteine 1893 and cysteine 1975
Cysteine 2096 and cysteine 2125
Cysteine 1994 and cysteine 2029
Cysteine 672 and cysteine 679
Cysteine 1378 and cysteine 1417
Cysteine 1957 and cysteine 1987
Cysteine 434 and cysteine 466
Cysteine 228 and cysteine 235
Cysteine 1850 and cysteine 1856
Cysteine 2039 and cysteine 2046
Cysteine 831 and cysteine 838
Cysteine 420 and cysteine 454
Cysteine 328 and cysteine 366
Cysteine 77 and cysteine 84
Cysteine 731 and cysteine 760
Cysteine 475 and cysteine 519
Cysteine 1903 and cysteine 1927
Cysteine 383 and cysteine 391
Cysteine 1429 and cysteine 1436
Cysteine 1804 and cysteine 1839
Cysteine 627 and cysteine 664
Cysteine 1236 and cysteine 1271
A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1470 and 1503.

Details

Redox score ?
89
PDB code
6um2
Structure name
structure of m-6-p/igfii receptor and igfii complex
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1470
Residue number B
1503
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1470 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1503 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1759 and 1792.

Details

Redox score ?
88
PDB code
6um2
Structure name
structure of m-6-p/igfii receptor and igfii complex
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1759
Residue number B
1792
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1759 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1792 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 883 and 918.

Details

Redox score ?
87
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
883
Residue number B
918
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 883 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 918 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 2082 and 2113.

Details

Redox score ?
87
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
2082
Residue number B
2113
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 2082 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2113 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1186 and 1214.

Details

Redox score ?
87
PDB code
6um2
Structure name
structure of m-6-p/igfii receptor and igfii complex
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
41
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1186
Residue number B
1214
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1186 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1214 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 117 and 149 (82 and 114 respectively in this structure).

Details

Redox score ?
87
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
117
Residue number B
149
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 117 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 149 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 581 and 614.

Details

Redox score ?
86
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
581
Residue number B
614
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 581 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 614 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1328 and 1358.

Details

Redox score ?
86
PDB code
6um2
Structure name
structure of m-6-p/igfii receptor and igfii complex
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1328
Residue number B
1358
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1328 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1358 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 984 and 995.

Details

Redox score ?
85
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
984
Residue number B
995
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 984 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 995 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 275 and 306 (240 and 271 respectively in this structure).

Details

Redox score ?
85
PDB code
6v02
Structure name
n-terminal 5 domains of ci-mpr
Structure deposition date
2019-11-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
275
Residue number B
306
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 275 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 306 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1485 and 1515.

Details

Redox score ?
85
PDB code
6um2
Structure name
structure of m-6-p/igfii receptor and igfii complex
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1485
Residue number B
1515
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1485 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1515 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 2241 and 2275.

Details

Redox score ?
85
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
2241
Residue number B
2275
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 2241 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2275 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1766 and 1795.

Details

Redox score ?
85
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1766
Residue number B
1795
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1766 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1795 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 2257 and 2287.

Details

Redox score ?
85
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
2257
Residue number B
2287
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 2257 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2287 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 134 and 161 (99 and 126 respectively in this structure).

Details

Redox score ?
85
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
134
Residue number B
161
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 134 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 161 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 2197 and 2203.

Details

Redox score ?
85
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
2197
Residue number B
2203
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 2197 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2203 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 540 and 547.

Details

Redox score ?
85
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
540
Residue number B
547
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 540 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 547 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1917 and 1942.

Details

Redox score ?
85
PDB code
2v5p
Structure name
complex structure of human igf2r domains 11-13 bound to igf-ii
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1917
Residue number B
1942
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1917 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1942 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1893 and 1975.

Details

Redox score ?
84
PDB code
2v5p
Structure name
complex structure of human igf2r domains 11-13 bound to igf-ii
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1893
Residue number B
1975
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1893 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1975 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 2096 and 2125.

Details

Redox score ?
84
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
2096
Residue number B
2125
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 2096 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2125 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1994 and 2029.

Details

Redox score ?
84
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1994
Residue number B
2029
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1994 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2029 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 672 and 679 (637 and 644 respectively in this structure).

Details

Redox score ?
84
PDB code
6v02
Structure name
n-terminal 5 domains of ci-mpr
Structure deposition date
2019-11-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
672
Residue number B
679
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 672 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 679 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1378 and 1417.

Details

Redox score ?
84
PDB code
6um2
Structure name
structure of m-6-p/igfii receptor and igfii complex
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1378
Residue number B
1417
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1378 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1417 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1957 and 1987.

Details

Redox score ?
83
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1957
Residue number B
1987
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1957 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1987 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 434 and 466 (399 and 431 respectively in this structure).

Details

Redox score ?
83
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
434
Residue number B
466
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 434 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 466 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 228 and 235 (193 and 200 respectively in this structure).

Details

Redox score ?
83
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
228
Residue number B
235
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 228 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 235 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1850 and 1856.

Details

Redox score ?
83
PDB code
2v5p
Structure name
complex structure of human igf2r domains 11-13 bound to igf-ii
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1850
Residue number B
1856
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1850 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1856 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 2039 and 2046.

Details

Redox score ?
83
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
2039
Residue number B
2046
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 2039 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2046 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 831 and 838.

Details

Redox score ?
83
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
831
Residue number B
838
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 831 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 838 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 420 and 454 (385 and 419 respectively in this structure).

Details

Redox score ?
83
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
3
Half-sphere exposure sum ?
47
Minimum pKa ?
8
% buried
36
Peptide accession
P11717
Residue number A
420
Residue number B
454
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 420 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 454 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 328 and 366 (293 and 331 respectively in this structure).

Details

Redox score ?
83
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
328
Residue number B
366
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 328 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 366 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 77 and 84 (42 and 49 respectively in this structure).

Details

Redox score ?
83
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
77
Residue number B
84
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 77 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 84 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 731 and 760 (696 and 725 respectively in this structure).

Details

Redox score ?
83
PDB code
6v02
Structure name
n-terminal 5 domains of ci-mpr
Structure deposition date
2019-11-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
731
Residue number B
760
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 731 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 760 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 475 and 519 (440 and 484 respectively in this structure).

Details

Redox score ?
83
PDB code
6p8i
Structure name
n-terminal 5 domains of igfiir
Structure deposition date
2019-06-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
475
Residue number B
519
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 475 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 519 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1903 and 1927.

Details

Redox score ?
82
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1903
Residue number B
1927
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1903 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1927 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 383 and 391 (339 and 347 respectively in this structure).

Details

Redox score ?
82
PDB code
1sz0
Structure name
n-terminal 3 domains of ci-mpr bound to mannose 6-phosphate
Structure deposition date
2004-04-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
383
Residue number B
391
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 383 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 391 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1429 and 1436.

Details

Redox score ?
82
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1429
Residue number B
1436
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1429 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1436 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1804 and 1839.

Details

Redox score ?
82
PDB code
2v5o
Structure name
structure of human igf2r domains 11-14
Structure deposition date
2007-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
1804
Residue number B
1839
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1804 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1839 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 627 and 664 (592 and 629 respectively in this structure).

Details

Redox score ?
82
PDB code
6v02
Structure name
n-terminal 5 domains of ci-mpr
Structure deposition date
2019-11-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P11717
Residue number A
627
Residue number B
664
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 627 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 664 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Cation-independent mannose-6-phosphate receptor between cysteines 1236 and 1271.

Details

Redox score ?
82
PDB code
6um1
Structure name
structure of m-6-p/igfii receptor at ph 4
Structure deposition date
2019-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P08169
Residue number A
1236
Residue number B
1271
Peptide name
Cation-independent mannose-6-phosphate receptor

Ligandability

Cysteine 1236 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1271 of Cation-independent mannose-6-phosphate receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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