B-cell antigen receptor complex-associated protein alpha chain

Intermolecular

Cysteine 119 and cysteine 136 of B-cell antigen receptor complex-associated protein beta chain

Intramolecular

A redox-regulated disulphide may form between cysteine 119 of B-cell antigen receptor complex-associated protein alpha chain and cysteine 136 of B-cell antigen receptor complex-associated protein beta chain.

Details

Redox score ?

PDB code

7xt6

Structure name

structure of a membrane protein m3

Structure deposition date

2022-05-16

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide A name

B-cell antigen receptor complex-associated protein alpha chain

Peptide B name

B-cell antigen receptor complex-associated protein beta chain

Peptide A accession

P11912

Peptide B accession

P40259

Peptide A residue number

119

Peptide B residue number

136

Ligandability

Cysteine 119 of B-cell antigen receptor complex-associated protein alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 136 of B-cell antigen receptor complex-associated protein beta chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within B-cell antigen receptor complex-associated protein alpha chain between cysteines 54 and 106.

Details

Redox score ?

PDB code

7wsp

Structure name

structure of a membrane protein m

Structure deposition date

2022-01-30

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

P11912

Residue number A

Residue number B

106

Peptide name

B-cell antigen receptor complex-associated protein alpha chain

Ligandability

Cysteine 54 of B-cell antigen receptor complex-associated protein alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 106 of B-cell antigen receptor complex-associated protein alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within B-cell antigen receptor complex-associated protein alpha chain between cysteines 106 and 119. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?