ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Bone morphogenetic protein 3

Intermolecular
Cysteine 436 and cysteine 436
Cysteine 436 and cysteine 437
Cysteine 436 and cysteine 399
Cysteine 370 and cysteine 436
Cysteine 436 and cysteine 469
Intramolecular
Cysteine 399 and cysteine 469
Cysteine 370 and cysteine 437
Cysteine 403 and cysteine 471
Cysteine 370 and cysteine 403
Cysteine 370 and cysteine 471
More...
Cysteine 370 and cysteine 469
Cysteine 437 and cysteine 469
Cysteine 399 and cysteine 437
Cysteine 403 and cysteine 437
Cysteine 370 and cysteine 399
Cysteine 437 and cysteine 471
Cysteine 403 and cysteine 436
Cysteine 403 and cysteine 469
Cysteine 469 and cysteine 471
Cysteine 399 and cysteine 403
Cysteine 399 and cysteine 471
Cysteine 436 and cysteine 471
A redox-regulated disulphide may form between two units of Bone morphogenetic protein 3 at cysteines 436 and 436 (74 and 74 respectively in this structure).

Details

Redox score ?
75
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
91
Minimum pKa ?
nan
% buried
nan
Peptide A name
Bone morphogenetic protein 3
Peptide B name
Bone morphogenetic protein 3
Peptide A accession
P12645
Peptide B accession
P12645
Peptide A residue number
436
Peptide B residue number
436

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Bone morphogenetic protein 3 at cysteines 436 and 437 (74 and 75 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
49
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide A name
Bone morphogenetic protein 3
Peptide B name
Bone morphogenetic protein 3
Peptide A accession
P12645
Peptide B accession
P12645
Peptide A residue number
436
Peptide B residue number
437

Ligandability

Cysteine 436 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 437 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Bone morphogenetic protein 3 at cysteines 436 and 399 (74 and 37 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
87
Minimum pKa ?
nan
% buried
nan
Peptide A name
Bone morphogenetic protein 3
Peptide B name
Bone morphogenetic protein 3
Peptide A accession
P12645
Peptide B accession
P12645
Peptide A residue number
436
Peptide B residue number
399

Ligandability

Cysteine 436 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 399 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Bone morphogenetic protein 3 at cysteines 370 and 436 (8 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide A name
Bone morphogenetic protein 3
Peptide B name
Bone morphogenetic protein 3
Peptide A accession
P12645
Peptide B accession
P12645
Peptide A residue number
370
Peptide B residue number
436

Ligandability

Cysteine 370 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 436 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Bone morphogenetic protein 3 at cysteines 436 and 469 (74 and 107 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide A name
Bone morphogenetic protein 3
Peptide B name
Bone morphogenetic protein 3
Peptide A accession
P12645
Peptide B accession
P12645
Peptide A residue number
436
Peptide B residue number
469

Ligandability

Cysteine 436 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 469 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 399 and 469 (37 and 107 respectively in this structure).

Details

Redox score ?
84
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
399
Residue number B
469
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 399 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 469 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 370 and 437 (8 and 75 respectively in this structure).

Details

Redox score ?
83
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
370
Residue number B
437
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 370 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 437 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 403 and 471 (41 and 109 respectively in this structure).

Details

Redox score ?
83
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
403
Residue number B
471
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 403 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 370 and 403 (8 and 41 respectively in this structure).

Details

Redox score ?
73
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
370
Residue number B
403
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 370 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 403 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 370 and 471 (8 and 109 respectively in this structure).

Details

Redox score ?
72
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
370
Residue number B
471
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 370 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 370 and 469 (8 and 107 respectively in this structure).

Details

Redox score ?
68
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
370
Residue number B
469
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 370 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 469 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 437 and 469 (75 and 107 respectively in this structure).

Details

Redox score ?
68
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
437
Residue number B
469
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 437 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 469 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 399 and 437 (37 and 75 respectively in this structure).

Details

Redox score ?
65
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
399
Residue number B
437
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 399 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 437 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 403 and 437 (41 and 75 respectively in this structure).

Details

Redox score ?
64
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
403
Residue number B
437
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 403 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 437 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 370 and 399 (8 and 37 respectively in this structure).

Details

Redox score ?
63
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
6
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
370
Residue number B
399
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 370 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 399 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 437 and 471 (75 and 109 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
6
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
437
Residue number B
471
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 437 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 403 and 436 (41 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
403
Residue number B
436
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 403 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 436 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 403 and 469 (41 and 107 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
403
Residue number B
469
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 403 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 469 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 469 and 471 (107 and 109 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
469
Residue number B
471
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 469 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 399 and 403 (37 and 41 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
399
Residue number B
403
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 399 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 403 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 399 and 471 (37 and 109 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
399
Residue number B
471
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 399 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bone morphogenetic protein 3 between cysteines 436 and 471 (74 and 109 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
2qcq
Structure name
crystal structure of bone morphogenetic protein-3 (bmp-3)
Structure deposition date
2007-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12645
Residue number A
436
Residue number B
471
Peptide name
Bone morphogenetic protein 3

Ligandability

Cysteine 436 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Bone morphogenetic protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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