Eosinophil cationic protein
Intramolecular
Cysteine 64 and cysteine 123
Cysteine 50 and cysteine 110
Cysteine 89 and cysteine 98
Cysteine 82 and cysteine 138
Cysteine 98 and cysteine 138
Cysteine 89 and cysteine 138
Cysteine 64 and cysteine 110
Cysteine 82 and cysteine 89
Cysteine 50 and cysteine 123
Cysteine 50 and cysteine 64
More...Cysteine 110 and cysteine 123
Cysteine 82 and cysteine 98
4a2o A 37 A 96
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 64 and 123 (37 and 96 respectively in this structure).
Details
Redox score ?
88
PDB code
4a2o
Structure name
structure of the human eosinophil cationic protein in complex with sulfate anions
Structure deposition date
2011-09-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
64
Residue number B
123
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 64 of Eosinophil cationic protein
Cysteine 123 of Eosinophil cationic protein
1h1h A 23 A 83
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 50 and 110 (23 and 83 respectively in this structure).
Details
Redox score ?
86
PDB code
1h1h
Structure name
crystal structure of eosinophil cationic protein in complex with 2', 5'-adp at 2
Structure deposition date
2002-07-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
50
Residue number B
110
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 50 of Eosinophil cationic protein
Cysteine 110 of Eosinophil cationic protein
1dyt A 62 A 71
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 89 and 98 (62 and 71 respectively in this structure).
Details
Redox score ?
86
PDB code
1dyt
Structure name
x-ray crystal structure of ecp (rnase 3) at 1
Structure deposition date
2000-02-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
89
Residue number B
98
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 89 of Eosinophil cationic protein
Cysteine 98 of Eosinophil cationic protein
1h1h A 55 A 111
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 82 and 138 (55 and 111 respectively in this structure).
Details
Redox score ?
84
PDB code
1h1h
Structure name
crystal structure of eosinophil cationic protein in complex with 2', 5'-adp at 2
Structure deposition date
2002-07-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
82
Residue number B
138
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 82 of Eosinophil cationic protein
Cysteine 138 of Eosinophil cationic protein
4oxb A 71 A 111
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 98 and 138 (71 and 111 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
4oxb
Structure name
structure of ecp with sulphate anions at 1
Structure deposition date
2014-02-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
98
Residue number B
138
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 98 of Eosinophil cationic protein
Cysteine 138 of Eosinophil cationic protein
4oxf A 62 A 111
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 89 and 138 (62 and 111 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
4oxf
Structure name
structure of ecp in complex with citrate ions at 1
Structure deposition date
2014-02-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
89
Residue number B
138
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 89 of Eosinophil cationic protein
Cysteine 138 of Eosinophil cationic protein
2kb5 A 37 A 83
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 64 and 110 (37 and 83 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2kb5
Structure name
solution nmr structure of eosinophil cationic protein/rnase 3
Structure deposition date
2008-11-20
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
64
Residue number B
110
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 64 of Eosinophil cationic protein
Cysteine 110 of Eosinophil cationic protein
2kb5 A 55 A 62
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 82 and 89 (55 and 62 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
2kb5
Structure name
solution nmr structure of eosinophil cationic protein/rnase 3
Structure deposition date
2008-11-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
82
Residue number B
89
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 82 of Eosinophil cationic protein
Cysteine 89 of Eosinophil cationic protein
2kb5 A 23 A 96
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 50 and 123 (23 and 96 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
2kb5
Structure name
solution nmr structure of eosinophil cationic protein/rnase 3
Structure deposition date
2008-11-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
50
Residue number B
123
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 50 of Eosinophil cationic protein
Cysteine 123 of Eosinophil cationic protein
2kb5 A 23 A 37
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 50 and 64 (23 and 37 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2kb5
Structure name
solution nmr structure of eosinophil cationic protein/rnase 3
Structure deposition date
2008-11-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
50
Residue number B
64
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 50 of Eosinophil cationic protein
Cysteine 64 of Eosinophil cationic protein
2kb5 A 83 A 96
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 110 and 123 (83 and 96 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2kb5
Structure name
solution nmr structure of eosinophil cationic protein/rnase 3
Structure deposition date
2008-11-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
110
Residue number B
123
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 110 of Eosinophil cationic protein
Cysteine 123 of Eosinophil cationic protein
4a2o B 55 B 71
A redox-regulated disulphide may form within Eosinophil cationic protein between cysteines 82 and 98 (55 and 71 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
4a2o
Structure name
structure of the human eosinophil cationic protein in complex with sulfate anions
Structure deposition date
2011-09-28
Thiol separation (Å)
10
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P12724
Residue number A
82
Residue number B
98
Peptide name
Eosinophil cationic protein
Ligandability
Cysteine 82 of Eosinophil cationic protein
Cysteine 98 of Eosinophil cationic protein
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