Complement component C6
Intramolecular
Cysteine 22 and cysteine 61
Cysteine 24 and cysteine 65
Cysteine 93 and cysteine 127
Cysteine 773 and cysteine 784
Cysteine 82 and cysteine 117
Cysteine 35 and cysteine 73
Cysteine 577 and cysteine 611
Cysteine 732 and cysteine 761
Cysteine 589 and cysteine 601
Cysteine 180 and cysteine 218
More...Cysteine 793 and cysteine 816
Cysteine 644 and cysteine 686
Cysteine 897 and cysteine 932
Cysteine 399 and cysteine 420
Cysteine 140 and cysteine 151
Cysteine 672 and cysteine 699 L
Cysteine 786 and cysteine 823
Cysteine 543 and cysteine 552
Cysteine 22 and cysteine 65
Cysteine 801 and cysteine 837
Cysteine 96 and cysteine 133
Cysteine 39 and cysteine 78
Cysteine 704 and cysteine 746
Cysteine 888 and cysteine 912
Cysteine 526 and cysteine 541
Cysteine 499 and cysteine 623
Cysteine 146 and cysteine 164
Cysteine 882 and cysteine 919
Cysteine 158 and cysteine 173
Cysteine 523 and cysteine 539
Cysteine 22 and cysteine 24
Cysteine 521 and cysteine 570
Cysteine 61 and cysteine 65
Cysteine 862 and cysteine 880
Cysteine 862 and cysteine 867
Cysteine 867 and cysteine 873
Cysteine 541 and cysteine 543
Cysteine 873 and cysteine 880
Cysteine 541 and cysteine 552
Cysteine 526 and cysteine 552
4a5w B 22 B 61
A redox-regulated disulphide may form within Complement component C6 between cysteines 22 and 61.
Details
Redox score ?
91
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
22
Residue number B
61
Peptide name
Complement component C6
Ligandability
Cysteine 22 of Complement component C6
Cysteine 61 of Complement component C6
4a5w B 24 B 65
A redox-regulated disulphide may form within Complement component C6 between cysteines 24 and 65.
Details
Redox score ?
90
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
24
Residue number B
65
Peptide name
Complement component C6
Ligandability
Cysteine 24 of Complement component C6
Cysteine 65 of Complement component C6
3t5o A 72 A 106
A redox-regulated disulphide may form within Complement component C6 between cysteines 93 and 127 (72 and 106 respectively in this structure).
Details
Redox score ?
89
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
93
Residue number B
127
Peptide name
Complement component C6
Ligandability
Cysteine 93 of Complement component C6
Cysteine 127 of Complement component C6
4e0s B 752 B 763
A redox-regulated disulphide may form within Complement component C6 between cysteines 773 and 784 (752 and 763 respectively in this structure).
Details
Redox score ?
89
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
34
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
773
Residue number B
784
Peptide name
Complement component C6
Ligandability
Cysteine 773 of Complement component C6
Cysteine 784 of Complement component C6
3t5o A 61 A 96
A redox-regulated disulphide may form within Complement component C6 between cysteines 82 and 117 (61 and 96 respectively in this structure).
Details
Redox score ?
89
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
82
Residue number B
117
Peptide name
Complement component C6
Ligandability
Cysteine 82 of Complement component C6
Cysteine 117 of Complement component C6
4a5w B 35 B 73
A redox-regulated disulphide may form within Complement component C6 between cysteines 35 and 73.
Details
Redox score ?
88
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
42
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
35
Residue number B
73
Peptide name
Complement component C6
Ligandability
Cysteine 35 of Complement component C6
Cysteine 73 of Complement component C6
3t5o A 556 A 590
A redox-regulated disulphide may form within Complement component C6 between cysteines 577 and 611 (556 and 590 respectively in this structure).
Details
Redox score ?
88
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
31
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
577
Residue number B
611
Peptide name
Complement component C6
Ligandability
Cysteine 577 of Complement component C6
Cysteine 611 of Complement component C6
4e0s B 711 B 740
A redox-regulated disulphide may form within Complement component C6 between cysteines 732 and 761 (711 and 740 respectively in this structure).
Details
Redox score ?
87
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
732
Residue number B
761
Peptide name
Complement component C6
Ligandability
Cysteine 732 of Complement component C6
Cysteine 761 of Complement component C6
3t5o A 568 A 580
A redox-regulated disulphide may form within Complement component C6 between cysteines 589 and 601 (568 and 580 respectively in this structure).
Details
Redox score ?
87
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
589
Residue number B
601
Peptide name
Complement component C6
Ligandability
Cysteine 589 of Complement component C6
Cysteine 601 of Complement component C6
4a5w B 180 B 218
A redox-regulated disulphide may form within Complement component C6 between cysteines 180 and 218.
Details
Redox score ?
87
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
180
Residue number B
218
Peptide name
Complement component C6
Ligandability
Cysteine 180 of Complement component C6
Cysteine 218 of Complement component C6
3t5o A 772 A 795
A redox-regulated disulphide may form within Complement component C6 between cysteines 793 and 816 (772 and 795 respectively in this structure).
Details
Redox score ?
87
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
793
Residue number B
816
Peptide name
Complement component C6
Ligandability
Cysteine 793 of Complement component C6
Cysteine 816 of Complement component C6
3t5o A 623 A 665
A redox-regulated disulphide may form within Complement component C6 between cysteines 644 and 686 (623 and 665 respectively in this structure).
Details
Redox score ?
86
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
644
Residue number B
686
Peptide name
Complement component C6
Ligandability
Cysteine 644 of Complement component C6
Cysteine 686 of Complement component C6
3t5o A 876 A 911
A redox-regulated disulphide may form within Complement component C6 between cysteines 897 and 932 (876 and 911 respectively in this structure).
Details
Redox score ?
86
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
897
Residue number B
932
Peptide name
Complement component C6
Ligandability
Cysteine 897 of Complement component C6
Cysteine 932 of Complement component C6
4a5w B 399 B 420
A redox-regulated disulphide may form within Complement component C6 between cysteines 399 and 420.
Details
Redox score ?
86
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
399
Residue number B
420
Peptide name
Complement component C6
Ligandability
Cysteine 399 of Complement component C6
Cysteine 420 of Complement component C6
4a5w B 140 B 151
A redox-regulated disulphide may form within Complement component C6 between cysteines 140 and 151.
Details
Redox score ?
86
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
140
Residue number B
151
Peptide name
Complement component C6
Ligandability
Cysteine 140 of Complement component C6
Cysteine 151 of Complement component C6
4e0s B 651 B 678
A redox-regulated disulphide may form within Complement component C6 between cysteines 672 and 699 (651 and 678 respectively in this structure).
Details
Redox score ?
85
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
672
Residue number B
699
Peptide name
Complement component C6
Ligandability
Cysteine 672 of Complement component C6
Cysteine 699 of Complement component C6
7q6c A 786 A 823
A redox-regulated disulphide may form within Complement component C6 between cysteines 786 and 823.
Details
Redox score ?
85
PDB code
7q6c
Structure name
complement c6 fim1-2 bound to cp010 antibody
Structure deposition date
2021-11-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
786
Residue number B
823
Peptide name
Complement component C6
Ligandability
Cysteine 786 of Complement component C6
Cysteine 823 of Complement component C6
4e0s B 522 B 531
A redox-regulated disulphide may form within Complement component C6 between cysteines 543 and 552 (522 and 531 respectively in this structure).
Details
Redox score ?
85
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
543
Residue number B
552
Peptide name
Complement component C6
Ligandability
Cysteine 543 of Complement component C6
Cysteine 552 of Complement component C6
4e0s B 1 B 44
A redox-regulated disulphide may form within Complement component C6 between cysteines 22 and 65 (1 and 44 respectively in this structure).
Details
Redox score ?
85
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
3
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
22
Residue number B
65
Peptide name
Complement component C6
Ligandability
Cysteine 22 of Complement component C6
Cysteine 65 of Complement component C6
7q6c A 801 A 837
A redox-regulated disulphide may form within Complement component C6 between cysteines 801 and 837.
Details
Redox score ?
84
PDB code
7q6c
Structure name
complement c6 fim1-2 bound to cp010 antibody
Structure deposition date
2021-11-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
801
Residue number B
837
Peptide name
Complement component C6
Ligandability
Cysteine 801 of Complement component C6
Cysteine 837 of Complement component C6
4e0s B 75 B 112
A redox-regulated disulphide may form within Complement component C6 between cysteines 96 and 133 (75 and 112 respectively in this structure).
Details
Redox score ?
84
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
96
Residue number B
133
Peptide name
Complement component C6
Ligandability
Cysteine 96 of Complement component C6
Cysteine 133 of Complement component C6
3t5o A 18 A 57
A redox-regulated disulphide may form within Complement component C6 between cysteines 39 and 78 (18 and 57 respectively in this structure).
Details
Redox score ?
84
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
42
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
39
Residue number B
78
Peptide name
Complement component C6
Ligandability
Cysteine 39 of Complement component C6
Cysteine 78 of Complement component C6
4e0s B 683 B 725
A redox-regulated disulphide may form within Complement component C6 between cysteines 704 and 746 (683 and 725 respectively in this structure).
Details
Redox score ?
84
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
704
Residue number B
746
Peptide name
Complement component C6
Ligandability
Cysteine 704 of Complement component C6
Cysteine 746 of Complement component C6
4e0s B 867 B 891
A redox-regulated disulphide may form within Complement component C6 between cysteines 888 and 912 (867 and 891 respectively in this structure).
Details
Redox score ?
84
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
888
Residue number B
912
Peptide name
Complement component C6
Ligandability
Cysteine 888 of Complement component C6
Cysteine 912 of Complement component C6
4a5w B 526 B 541
A redox-regulated disulphide may form within Complement component C6 between cysteines 526 and 541.
Details
Redox score ?
83
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
526
Residue number B
541
Peptide name
Complement component C6
Ligandability
Cysteine 526 of Complement component C6
Cysteine 541 of Complement component C6
4e0s B 478 B 602
A redox-regulated disulphide may form within Complement component C6 between cysteines 499 and 623 (478 and 602 respectively in this structure).
Details
Redox score ?
83
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
499
Residue number B
623
Peptide name
Complement component C6
Ligandability
Cysteine 499 of Complement component C6
Cysteine 623 of Complement component C6
4e0s B 125 B 143
A redox-regulated disulphide may form within Complement component C6 between cysteines 146 and 164 (125 and 143 respectively in this structure).
Details
Redox score ?
82
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
146
Residue number B
164
Peptide name
Complement component C6
Ligandability
Cysteine 146 of Complement component C6
Cysteine 164 of Complement component C6
7q6c A 882 A 919
A redox-regulated disulphide may form within Complement component C6 between cysteines 882 and 919.
Details
Redox score ?
82
PDB code
7q6c
Structure name
complement c6 fim1-2 bound to cp010 antibody
Structure deposition date
2021-11-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
882
Residue number B
919
Peptide name
Complement component C6
Ligandability
Cysteine 882 of Complement component C6
Cysteine 919 of Complement component C6
4e0s B 137 B 152
A redox-regulated disulphide may form within Complement component C6 between cysteines 158 and 173 (137 and 152 respectively in this structure).
Details
Redox score ?
81
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
158
Residue number B
173
Peptide name
Complement component C6
Ligandability
Cysteine 158 of Complement component C6
Cysteine 173 of Complement component C6
3t5o A 502 A 518
A redox-regulated disulphide may form within Complement component C6 between cysteines 523 and 539 (502 and 518 respectively in this structure).
Details
Redox score ?
81
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
523
Residue number B
539
Peptide name
Complement component C6
Ligandability
Cysteine 523 of Complement component C6
Cysteine 539 of Complement component C6
4e0s B 1 B 3
A redox-regulated disulphide may form within Complement component C6 between cysteines 22 and 24 (1 and 3 respectively in this structure).
Details
Redox score ?
80
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
22
Residue number B
24
Peptide name
Complement component C6
Ligandability
Cysteine 22 of Complement component C6
Cysteine 24 of Complement component C6
4a5w B 521 B 570
A redox-regulated disulphide may form within Complement component C6 between cysteines 521 and 570.
Details
Redox score ?
80
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
521
Residue number B
570
Peptide name
Complement component C6
Ligandability
Cysteine 521 of Complement component C6
Cysteine 570 of Complement component C6
3t5o A 40 A 44
A redox-regulated disulphide may form within Complement component C6 between cysteines 61 and 65 (40 and 44 respectively in this structure).
Details
Redox score ?
76
PDB code
3t5o
Structure name
crystal structure of human complement component c6
Structure deposition date
2011-07-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
61
Residue number B
65
Peptide name
Complement component C6
Ligandability
Cysteine 61 of Complement component C6
Cysteine 65 of Complement component C6
7q6c A 862 A 880
A redox-regulated disulphide may form within Complement component C6 between cysteines 862 and 880.
Details
Redox score ?
72
PDB code
7q6c
Structure name
complement c6 fim1-2 bound to cp010 antibody
Structure deposition date
2021-11-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
862
Residue number B
880
Peptide name
Complement component C6
Ligandability
Cysteine 862 of Complement component C6
Cysteine 880 of Complement component C6
4e0s B 841 B 846
A redox-regulated disulphide may form within Complement component C6 between cysteines 862 and 867 (841 and 846 respectively in this structure).
Details
Redox score ?
71
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
862
Residue number B
867
Peptide name
Complement component C6
Ligandability
Cysteine 862 of Complement component C6
Cysteine 867 of Complement component C6
4e0s B 846 B 852
A redox-regulated disulphide may form within Complement component C6 between cysteines 867 and 873 (846 and 852 respectively in this structure).
Details
Redox score ?
71
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
867
Residue number B
873
Peptide name
Complement component C6
Ligandability
Cysteine 867 of Complement component C6
Cysteine 873 of Complement component C6
4a5w B 541 B 543
A redox-regulated disulphide may form within Complement component C6 between cysteines 541 and 543.
Details
Redox score ?
70
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
541
Residue number B
543
Peptide name
Complement component C6
Ligandability
Cysteine 541 of Complement component C6
Cysteine 543 of Complement component C6
4e0s B 852 B 859
A redox-regulated disulphide may form within Complement component C6 between cysteines 873 and 880 (852 and 859 respectively in this structure).
Details
Redox score ?
69
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
873
Residue number B
880
Peptide name
Complement component C6
Ligandability
Cysteine 873 of Complement component C6
Cysteine 880 of Complement component C6
4a5w B 541 B 552
A redox-regulated disulphide may form within Complement component C6 between cysteines 541 and 552.
Details
Redox score ?
68
PDB code
4a5w
Structure name
crystal structure of c5b6
Structure deposition date
2011-10-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
541
Residue number B
552
Peptide name
Complement component C6
Ligandability
Cysteine 541 of Complement component C6
Cysteine 552 of Complement component C6
4e0s B 505 B 531
A redox-regulated disulphide may form within Complement component C6 between cysteines 526 and 552 (505 and 531 respectively in this structure).
Details
Redox score ?
63
PDB code
4e0s
Structure name
crystal structure of c5b-6
Structure deposition date
2012-03-05
Thiol separation (Å)
6
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P13671
Residue number A
526
Residue number B
552
Peptide name
Complement component C6
Ligandability
Cysteine 526 of Complement component C6
Cysteine 552 of Complement component C6
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