a tool for identifying drug-targetable redox-active disulphides

Annexin A8

Intramolecular

Cysteine 161 and cysteine 206

A redox-regulated disulphide may form within Annexin A8 between cysteines 161 and 206.

Details

Redox score ?

82

PDB code

Structure name

the 2

Structure deposition date

2004-07-22

Thiol separation (Å)

2

Half-sphere exposure sum ?

67

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

161

Residue number B

206

Peptide name

Annexin A8

Ligandability

Cysteine 161 of Annexin A8

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 206 of Annexin A8

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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