Aldo-keto reductase family 1 member A1

Intramolecular

A redox-regulated disulphide may form within Aldo-keto reductase family 1 member A1 between cysteines 187 and 260. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4gac

Structure name

high resolution structure of mouse aldehyde reductase (akr1a4) in its apo-form

Structure deposition date

2012-07-25

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

Q9JII6

Residue number A

187

Residue number B

260

Peptide name

Aldo-keto reductase family 1 member A1

Ligandability

Cysteine 187 of Aldo-keto reductase family 1 member A1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.