ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Junction plakoglobin

Intramolecular
Cysteine 420 and cysteine 457
A redox-regulated disulphide may form within Junction plakoglobin between cysteines 420 and 457. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
30
PDB code
3ifq
Structure name
interction of plakoglobin and beta-catenin with desmosomal cadherins
Structure deposition date
2009-07-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
97
Minimum pKa ?
11
% buried
92
Peptide accession
P14923
Residue number A
420
Residue number B
457
Peptide name
Junction plakoglobin

Ligandability

Cysteine 420 of Junction plakoglobin

Cysteine 457 of Junction plakoglobin

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