Interleukin-9
Intermolecular
Cysteine 56 and cysteine 56
Cysteine 47 and cysteine 56
Cysteine 47 and cysteine 47
Intramolecular
Cysteine 21 and cysteine 104
Cysteine 45 and cysteine 54
Cysteine 68 and cysteine 109
Cysteine 64 and cysteine 113
Cysteine 47 and cysteine 54
Cysteine 45 and cysteine 47
Cysteine 54 and cysteine 56
More...Cysteine 45 and cysteine 56
Cysteine 68 and cysteine 113
Cysteine 109 and cysteine 113
Cysteine 64 and cysteine 68
Cysteine 64 and cysteine 109
Cysteine 104 and cysteine 109
7ox2 T 56 M 56
A redox-regulated disulphide may form between two units of Interleukin-9 at cysteines 56 and 56.
Details
Redox score ?
70
PDB code
7ox2
Structure name
fab 6e2: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
93
Minimum pKa ?
nan
% buried
nan
Peptide A name
Interleukin-9
Peptide B name
Interleukin-9
Peptide A accession
P15248
Peptide B accession
P15248
Peptide A residue number
56
Peptide B residue number
56
Ligandability
7ox2 O 47 N 56
A redox-regulated disulphide may form between two units of Interleukin-9 at cysteines 47 and 56.
Details
Redox score ?
63
PDB code
7ox2
Structure name
fab 6e2: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
6
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide A name
Interleukin-9
Peptide B name
Interleukin-9
Peptide A accession
P15248
Peptide B accession
P15248
Peptide A residue number
47
Peptide B residue number
56
Ligandability
Cysteine 47 of Interleukin-9
Cysteine 56 of Interleukin-9
7ox2 O 47 N 47
A redox-regulated disulphide may form between two units of Interleukin-9 at cysteines 47 and 47. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
7ox2
Structure name
fab 6e2: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide A name
Interleukin-9
Peptide B name
Interleukin-9
Peptide A accession
P15248
Peptide B accession
P15248
Peptide A residue number
47
Peptide B residue number
47
Ligandability
7ox1 X 21 X 104
A redox-regulated disulphide may form within Interleukin-9 between cysteines 21 and 104.
Details
Redox score ?
86
PDB code
7ox1
Structure name
fab 7d6: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
21
Residue number B
104
Peptide name
Interleukin-9
Ligandability
Cysteine 21 of Interleukin-9
Cysteine 104 of Interleukin-9
7ox2 M 45 M 54
A redox-regulated disulphide may form within Interleukin-9 between cysteines 45 and 54.
Details
Redox score ?
80
PDB code
7ox2
Structure name
fab 6e2: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
45
Residue number B
54
Peptide name
Interleukin-9
Ligandability
Cysteine 45 of Interleukin-9
Cysteine 54 of Interleukin-9
7ox1 X 68 X 109
A redox-regulated disulphide may form within Interleukin-9 between cysteines 68 and 109.
Details
Redox score ?
78
PDB code
7ox1
Structure name
fab 7d6: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
9
% buried
9
Peptide accession
P15248
Residue number A
68
Residue number B
109
Peptide name
Interleukin-9
Ligandability
Cysteine 68 of Interleukin-9
Cysteine 109 of Interleukin-9
7ox2 N 64 N 113
A redox-regulated disulphide may form within Interleukin-9 between cysteines 64 and 113.
Details
Redox score ?
76
PDB code
7ox2
Structure name
fab 6e2: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
9
% buried
6
Peptide accession
P15248
Residue number A
64
Residue number B
113
Peptide name
Interleukin-9
Ligandability
Cysteine 64 of Interleukin-9
Cysteine 113 of Interleukin-9
7ox5 L 47 L 54
A redox-regulated disulphide may form within Interleukin-9 between cysteines 47 and 54.
Details
Redox score ?
74
PDB code
7ox5
Structure name
hil-9:hil-9ra complex
Structure deposition date
2021-06-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
47
Residue number B
54
Peptide name
Interleukin-9
Ligandability
Cysteine 47 of Interleukin-9
Cysteine 54 of Interleukin-9
7ox1 Z 45 Z 47
A redox-regulated disulphide may form within Interleukin-9 between cysteines 45 and 47.
Details
Redox score ?
74
PDB code
7ox1
Structure name
fab 7d6: hil-9 complex
Structure deposition date
2021-06-22
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
45
Residue number B
47
Peptide name
Interleukin-9
Ligandability
Cysteine 45 of Interleukin-9
Cysteine 47 of Interleukin-9
7ox5 L 54 L 56
A redox-regulated disulphide may form within Interleukin-9 between cysteines 54 and 56.
Details
Redox score ?
66
PDB code
7ox5
Structure name
hil-9:hil-9ra complex
Structure deposition date
2021-06-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
54
Residue number B
56
Peptide name
Interleukin-9
Ligandability
Cysteine 54 of Interleukin-9
Cysteine 56 of Interleukin-9
7ox5 D 45 D 56
A redox-regulated disulphide may form within Interleukin-9 between cysteines 45 and 56. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
7ox5
Structure name
hil-9:hil-9ra complex
Structure deposition date
2021-06-22
Thiol separation (Å)
6
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
45
Residue number B
56
Peptide name
Interleukin-9
Ligandability
Cysteine 45 of Interleukin-9
Cysteine 56 of Interleukin-9
7ox5 P 68 P 113
A redox-regulated disulphide may form within Interleukin-9 between cysteines 68 and 113. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
7ox5
Structure name
hil-9:hil-9ra complex
Structure deposition date
2021-06-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
20
Peptide accession
P15248
Residue number A
68
Residue number B
113
Peptide name
Interleukin-9
Ligandability
Cysteine 68 of Interleukin-9
Cysteine 113 of Interleukin-9
7ox5 H 109 H 113
A redox-regulated disulphide may form within Interleukin-9 between cysteines 109 and 113. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7ox5
Structure name
hil-9:hil-9ra complex
Structure deposition date
2021-06-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
109
Residue number B
113
Peptide name
Interleukin-9
Ligandability
Cysteine 109 of Interleukin-9
Cysteine 113 of Interleukin-9
7ox5 H 64 H 68
A redox-regulated disulphide may form within Interleukin-9 between cysteines 64 and 68. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7ox5
Structure name
hil-9:hil-9ra complex
Structure deposition date
2021-06-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
64
Residue number B
68
Peptide name
Interleukin-9
Ligandability
Cysteine 64 of Interleukin-9
Cysteine 68 of Interleukin-9
7ox5 H 64 H 109
A redox-regulated disulphide may form within Interleukin-9 between cysteines 64 and 109. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
7ox5
Structure name
hil-9:hil-9ra complex
Structure deposition date
2021-06-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
64
Residue number B
109
Peptide name
Interleukin-9
Ligandability
Cysteine 64 of Interleukin-9
Cysteine 109 of Interleukin-9
7ox6 A 104 A 109
A redox-regulated disulphide may form within Interleukin-9 between cysteines 104 and 109. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
7ox6
Structure name
solution structure of human interleukin-9
Structure deposition date
2021-06-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15248
Residue number A
104
Residue number B
109
Peptide name
Interleukin-9
Ligandability
Cysteine 104 of Interleukin-9
Cysteine 109 of Interleukin-9
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