ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Cyclic AMP-dependent transcription factor ATF-2

Intramolecular
Cysteine 27 and cysteine 32
A redox-regulated disulphide may form within Cyclic AMP-dependent transcription factor ATF-2 between cysteines 27 and 32 (9 and 14 respectively in this structure).

Details

Redox score ?
74
PDB code
1bhi
Structure name
structure of transactivation domain of cre-bp1/atf-2, nmr, 20 structures
Structure deposition date
1998-06-09
Thiol separation (Å)
5
Half-sphere exposure sum ?
39
Minimum pKa ?
9
% buried
0
Peptide accession
P15336
Residue number A
27
Residue number B
32
Peptide name
Cyclic AMP-dependent transcription factor ATF-2

Ligandability

Cysteine 27 of Cyclic AMP-dependent transcription factor ATF-2

Cysteine 32 of Cyclic AMP-dependent transcription factor ATF-2

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