ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

B-lymphocyte antigen CD19

Intramolecular
Cysteine 134 and cysteine 173
Cysteine 38 and cysteine 261
Cysteine 97 and cysteine 200
A redox-regulated disulphide may form within B-lymphocyte antigen CD19 between cysteines 134 and 173.

Details

Redox score ?
87
PDB code
6al5
Structure name
complex between cd19 (n138q mutant) and b43 fab
Structure deposition date
2017-08-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
31
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15391
Residue number A
134
Residue number B
173
Peptide name
B-lymphocyte antigen CD19

Ligandability

Cysteine 134 of B-lymphocyte antigen CD19

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 173 of B-lymphocyte antigen CD19

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within B-lymphocyte antigen CD19 between cysteines 38 and 261.

Details

Redox score ?
82
PDB code
6al5
Structure name
complex between cd19 (n138q mutant) and b43 fab
Structure deposition date
2017-08-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15391
Residue number A
38
Residue number B
261
Peptide name
B-lymphocyte antigen CD19

Ligandability

Cysteine 38 of B-lymphocyte antigen CD19

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 261 of B-lymphocyte antigen CD19

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within B-lymphocyte antigen CD19 between cysteines 97 and 200.

Details

Redox score ?
81
PDB code
6al5
Structure name
complex between cd19 (n138q mutant) and b43 fab
Structure deposition date
2017-08-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P15391
Residue number A
97
Residue number B
200
Peptide name
B-lymphocyte antigen CD19

Ligandability

Cysteine 97 of B-lymphocyte antigen CD19

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 200 of B-lymphocyte antigen CD19

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: